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Antiulcer Agents: From Plant Extracts to Phytochemicals in Healing Promotion
In this narrative review, we have comprehensively reviewed the plant sources used as antiulcer agents. From traditional uses as herbal remedies, we have moved on to preclinical evidence, critically discussing the in vitro and in vivo studies focusing on plant extracts and even isolated phytochemical...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100067/ https://www.ncbi.nlm.nih.gov/pubmed/30018251 http://dx.doi.org/10.3390/molecules23071751 |
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author | Sharifi-Rad, Mehdi Fokou, Patrick Valere Tsouh Sharopov, Farukh Martorell, Miquel Ademiluyi, Adedayo Oluwaseun Rajkovic, Jovana Salehi, Bahare Martins, Natália Iriti, Marcello Sharifi-Rad, Javad |
author_facet | Sharifi-Rad, Mehdi Fokou, Patrick Valere Tsouh Sharopov, Farukh Martorell, Miquel Ademiluyi, Adedayo Oluwaseun Rajkovic, Jovana Salehi, Bahare Martins, Natália Iriti, Marcello Sharifi-Rad, Javad |
author_sort | Sharifi-Rad, Mehdi |
collection | PubMed |
description | In this narrative review, we have comprehensively reviewed the plant sources used as antiulcer agents. From traditional uses as herbal remedies, we have moved on to preclinical evidence, critically discussing the in vitro and in vivo studies focusing on plant extracts and even isolated phytochemicals with antiulcerogenic potential. A particular emphasis was also paid to Helicobacter pylori activity, with emphasis on involved mechanisms of action. Lastly, the issue of safety profile of these plant products has also been addressed. |
format | Online Article Text |
id | pubmed-6100067 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-61000672018-11-13 Antiulcer Agents: From Plant Extracts to Phytochemicals in Healing Promotion Sharifi-Rad, Mehdi Fokou, Patrick Valere Tsouh Sharopov, Farukh Martorell, Miquel Ademiluyi, Adedayo Oluwaseun Rajkovic, Jovana Salehi, Bahare Martins, Natália Iriti, Marcello Sharifi-Rad, Javad Molecules Review In this narrative review, we have comprehensively reviewed the plant sources used as antiulcer agents. From traditional uses as herbal remedies, we have moved on to preclinical evidence, critically discussing the in vitro and in vivo studies focusing on plant extracts and even isolated phytochemicals with antiulcerogenic potential. A particular emphasis was also paid to Helicobacter pylori activity, with emphasis on involved mechanisms of action. Lastly, the issue of safety profile of these plant products has also been addressed. MDPI 2018-07-17 /pmc/articles/PMC6100067/ /pubmed/30018251 http://dx.doi.org/10.3390/molecules23071751 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Sharifi-Rad, Mehdi Fokou, Patrick Valere Tsouh Sharopov, Farukh Martorell, Miquel Ademiluyi, Adedayo Oluwaseun Rajkovic, Jovana Salehi, Bahare Martins, Natália Iriti, Marcello Sharifi-Rad, Javad Antiulcer Agents: From Plant Extracts to Phytochemicals in Healing Promotion |
title | Antiulcer Agents: From Plant Extracts to Phytochemicals in Healing Promotion |
title_full | Antiulcer Agents: From Plant Extracts to Phytochemicals in Healing Promotion |
title_fullStr | Antiulcer Agents: From Plant Extracts to Phytochemicals in Healing Promotion |
title_full_unstemmed | Antiulcer Agents: From Plant Extracts to Phytochemicals in Healing Promotion |
title_short | Antiulcer Agents: From Plant Extracts to Phytochemicals in Healing Promotion |
title_sort | antiulcer agents: from plant extracts to phytochemicals in healing promotion |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100067/ https://www.ncbi.nlm.nih.gov/pubmed/30018251 http://dx.doi.org/10.3390/molecules23071751 |
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