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Antiulcer Agents: From Plant Extracts to Phytochemicals in Healing Promotion

In this narrative review, we have comprehensively reviewed the plant sources used as antiulcer agents. From traditional uses as herbal remedies, we have moved on to preclinical evidence, critically discussing the in vitro and in vivo studies focusing on plant extracts and even isolated phytochemical...

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Detalles Bibliográficos
Autores principales: Sharifi-Rad, Mehdi, Fokou, Patrick Valere Tsouh, Sharopov, Farukh, Martorell, Miquel, Ademiluyi, Adedayo Oluwaseun, Rajkovic, Jovana, Salehi, Bahare, Martins, Natália, Iriti, Marcello, Sharifi-Rad, Javad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100067/
https://www.ncbi.nlm.nih.gov/pubmed/30018251
http://dx.doi.org/10.3390/molecules23071751
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author Sharifi-Rad, Mehdi
Fokou, Patrick Valere Tsouh
Sharopov, Farukh
Martorell, Miquel
Ademiluyi, Adedayo Oluwaseun
Rajkovic, Jovana
Salehi, Bahare
Martins, Natália
Iriti, Marcello
Sharifi-Rad, Javad
author_facet Sharifi-Rad, Mehdi
Fokou, Patrick Valere Tsouh
Sharopov, Farukh
Martorell, Miquel
Ademiluyi, Adedayo Oluwaseun
Rajkovic, Jovana
Salehi, Bahare
Martins, Natália
Iriti, Marcello
Sharifi-Rad, Javad
author_sort Sharifi-Rad, Mehdi
collection PubMed
description In this narrative review, we have comprehensively reviewed the plant sources used as antiulcer agents. From traditional uses as herbal remedies, we have moved on to preclinical evidence, critically discussing the in vitro and in vivo studies focusing on plant extracts and even isolated phytochemicals with antiulcerogenic potential. A particular emphasis was also paid to Helicobacter pylori activity, with emphasis on involved mechanisms of action. Lastly, the issue of safety profile of these plant products has also been addressed.
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spelling pubmed-61000672018-11-13 Antiulcer Agents: From Plant Extracts to Phytochemicals in Healing Promotion Sharifi-Rad, Mehdi Fokou, Patrick Valere Tsouh Sharopov, Farukh Martorell, Miquel Ademiluyi, Adedayo Oluwaseun Rajkovic, Jovana Salehi, Bahare Martins, Natália Iriti, Marcello Sharifi-Rad, Javad Molecules Review In this narrative review, we have comprehensively reviewed the plant sources used as antiulcer agents. From traditional uses as herbal remedies, we have moved on to preclinical evidence, critically discussing the in vitro and in vivo studies focusing on plant extracts and even isolated phytochemicals with antiulcerogenic potential. A particular emphasis was also paid to Helicobacter pylori activity, with emphasis on involved mechanisms of action. Lastly, the issue of safety profile of these plant products has also been addressed. MDPI 2018-07-17 /pmc/articles/PMC6100067/ /pubmed/30018251 http://dx.doi.org/10.3390/molecules23071751 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Sharifi-Rad, Mehdi
Fokou, Patrick Valere Tsouh
Sharopov, Farukh
Martorell, Miquel
Ademiluyi, Adedayo Oluwaseun
Rajkovic, Jovana
Salehi, Bahare
Martins, Natália
Iriti, Marcello
Sharifi-Rad, Javad
Antiulcer Agents: From Plant Extracts to Phytochemicals in Healing Promotion
title Antiulcer Agents: From Plant Extracts to Phytochemicals in Healing Promotion
title_full Antiulcer Agents: From Plant Extracts to Phytochemicals in Healing Promotion
title_fullStr Antiulcer Agents: From Plant Extracts to Phytochemicals in Healing Promotion
title_full_unstemmed Antiulcer Agents: From Plant Extracts to Phytochemicals in Healing Promotion
title_short Antiulcer Agents: From Plant Extracts to Phytochemicals in Healing Promotion
title_sort antiulcer agents: from plant extracts to phytochemicals in healing promotion
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100067/
https://www.ncbi.nlm.nih.gov/pubmed/30018251
http://dx.doi.org/10.3390/molecules23071751
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