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Synthesis and Comparative Evaluation of Novel Cationic Amphiphile C12-Man-Q as an Efficient DNA Delivery Agent In Vitro

New amphiphilic 1,4-DHP derivative C12-Man-Q with remoted cationic moieties at positions 2 and 6 was synthesised to study DNA delivery activity. The results were compared with data obtained for cationic 1,4-DHP derivative D19, which is known to be the most efficient one among the previously tested 1...

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Detalles Bibliográficos
Autores principales:	Apsite, Gunita, Timofejeva, Irena, Vezane, Aleksandra, Vigante, Brigita, Rucins, Martins, Sobolev, Arkadij, Plotniece, Mara, Pajuste, Karlis, Kozlovska, Tatjana, Plotniece, Aiva
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100083/ https://www.ncbi.nlm.nih.gov/pubmed/29949910 http://dx.doi.org/10.3390/molecules23071540

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