Cargando…

Novel Pyrazole-Hydrazone Derivatives Containing an Isoxazole Moiety: Design, Synthesis, and Antiviral Activity

In this study, a series of novel pyrazole-hydrazone derivatives containing an isoxazole moiety were synthesized. Antiviral bioassays indicated that some of the title compounds exhibited better in vivo antiviral activities against tobacco mosaic virus (TMV). In particular, compounds 6a, 6c and 6q exh...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, Zaibo, Li, Pei, Gan, Xiuhai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100116/ https://www.ncbi.nlm.nih.gov/pubmed/30037021 http://dx.doi.org/10.3390/molecules23071798

Ejemplares similares

Synthesis, Antiviral Bioactivity of Novel 4-Thioquinazoline Derivatives Containing Chalcone Moiety
por: Wan, Zhihua, et al.
Publicado: (2015)

Design, Synthesis, and Bioactivity Evaluation of Novel Isoxazole-Amide Derivatives Containing an Acylhydrazone Moiety as New Active Antiviral Agents
por: Yang, Zai-Bo, et al.
Publicado: (2019)

Design, Synthesis and Bioactivities of Novel Isoxazole-Containing Pyrazole Oxime Derivatives
por: Dai, Hong, et al.
Publicado: (2017)

Novel Thiochromanone Derivatives Containing a Sulfonyl Hydrazone Moiety: Design, Synthesis, and Bioactivity Evaluation
por: Yu, Lu, et al.
Publicado: (2021)

Synthesis and antifungal activity of novel pyrazolecarboxamide derivatives containing a hydrazone moiety
por: Wu, Jian, et al.
Publicado: (2012)

Design, Synthesis, and Biological Activity of Novel Chalcone Derivatives Containing an 1,2,4-Oxadiazole Moiety
por: Luo, Ling, et al.
Publicado: (2022)

Synthesis of Novel Pyrazole Derivatives Containing Phenylpyridine Moieties with Herbicidal Activity
por: Cai, Zengfei, et al.
Publicado: (2022)

Synthesis and Antiviral Activity of Novel 1,4-Pentadien-3-one Derivatives Containing a 1,3,4-Thiadiazole Moiety
por: Yu, Lu, et al.
Publicado: (2017)

Synthesis and antibacterial activity against ralstonia solanacearum for novel hydrazone derivatives containing a pyridine moiety
por: Wu, Jian, et al.
Publicado: (2012)

Synthesis and Antimicrobial Evaluation of Some Novel Thiazole, Pyridone, Pyrazole, Chromene, Hydrazone Derivatives Bearing a Biologically Active Sulfonamide Moiety
por: Darwish, Elham S., et al.
Publicado: (2014)

Synthesis of Tricyclic Condensed Rings Incorporating the Pyrazole or Isoxazole Moieties Bonded to a 4-Piperidinyl Substituent
por: Pinna, Giansalvo, et al.
Publicado: (2013)

Synthesis and Bioactivities of Novel Pyrazole Oxime Derivatives Containing a 5-Trifluoromethylpyridyl Moiety
por: Dai, Hong, et al.
Publicado: (2016)

Synthesis and investigation of antimicrobial activities of nitrofurazone analogues containing hydrazide-hydrazone moiety
por: Popiołek, Łukasz, et al.
Publicado: (2017)

Synthesis and Biological Evaluation of Novel Hybrid Molecules Containing Purine, Coumarin and Isoxazoline or Isoxazole Moieties
por: Kallitsakis, Michael G., et al.
Publicado: (2017)

Synthesis and cellular bioactivities of novel isoxazole derivatives incorporating an arylpiperazine moiety as anticancer agents
por: Çalışkan, Burcu, et al.
Publicado: (2018)

Design, Synthesis, and Biological Activities of Novel Pyrazole Oxime Compounds Containing a Substituted Pyridyl Moiety
por: Chen, Cuili, et al.
Publicado: (2017)

Synthesis and Cytotoxic Activity of Novel Tetrahydrocurcumin Derivatives Bearing Pyrazole Moiety
por: Mahal, Ahmed, et al.
Publicado: (2017)

Phenanthrotriazine Derivatives Containing Arylidine Hydrazone Moieties as Novel Potential c-Met Inhibitors with Anticancer Effect
por: Edraki, Najmeh, et al.
Publicado: (2021)

Design, Synthesis, Antibacterial Activity, Antiviral Activity, and Mechanism of Myricetin Derivatives Containing a Quinazolinone Moiety
por: Liu, Tingting, et al.
Publicado: (2021)

Novel chalcone derivatives containing a 1,2,4-triazine moiety: design, synthesis, antibacterial and antiviral activities
por: Tang, Xu, et al.
Publicado: (2019)

Synthesis and Bioactivity of Hydrazide-Hydrazones with the 1-Adamantyl-Carbonyl Moiety
por: Pham, Van Hien, et al.
Publicado: (2019)

Synthesis of Novel 3H-Quinazolin-4-ones Containing Pyrazolinone, Pyrazole and Pyrimidinone Moieties
por: Saleh, Mohamed A., et al.
Publicado: (2003)

Clean Grinding Technique: A Facile Synthesis and In Silico Antiviral Activity of Hydrazones, Pyrazoles, and Pyrazines Bearing Thiazole Moiety against SARS-CoV-2 Main Protease (M(pro))
por: Abu-Melha, Sraa, et al.
Publicado: (2020)

The spectrogram data of quinazoline derivatives containing a dithioacetal moiety
por: Xie, Dandan, et al.
Publicado: (2018)

Synthesis, antimycobacterial screening, molecular docking, ADMET prediction and pharmacological evaluation on novel pyran-4-one bearing hydrazone, triazole and isoxazole moieties: Potential inhibitors of SARS CoV-2
por: Ravisankar, N., et al.
Publicado: (2023)

Design, Synthesis, and Antifungal Activity of Some Novel Phenylthiazole Derivatives Containing an Acylhydrazone Moiety
por: Tian, Yao, et al.
Publicado: (2023)

Design, synthesis and evaluation of anticancer activity of novel 2-thioxoimidazolidin-4-one derivatives bearing pyrazole, triazole and benzoxazole moieties
por: Elhady, Heba A., et al.
Publicado: (2018)

Design, synthesis and biological activities of echinopsine derivatives containing acylhydrazone moiety
por: Cui, Peipei, et al.
Publicado: (2022)

Design, Synthesis, and Antitumor Activity of Olmutinib Derivatives Containing Acrylamide Moiety
por: Hu, Xiaohan, et al.
Publicado: (2021)

Design, Synthesis, Antiviral Bioactivity, and Mechanism of the Ferulic Acid Ester-Containing Sulfonamide Moiety
por: Ren, Xiaoli, et al.
Publicado: (2020)

Design, Synthesis and Antifungal/Nematicidal Activity of Novel 1,2,4-Oxadiazole Derivatives Containing Amide Fragments
por: Liu, Dan, et al.
Publicado: (2022)

Design, Synthesis and Mechanistic Studies of Novel Isatin-Pyrazole Hydrazone Conjugates as Selective and Potent Bacterial MetAP Inhibitors
por: Irfan, Iram, et al.
Publicado: (2022)

Design, synthesis and fungicidal evaluation of novel psoralen derivatives containing sulfonohydrazide or acylthiourea moiety
por: Dong, Jingyue, et al.
Publicado: (2022)

Design, Synthesis, and Bioactivity Study of Novel Tryptophan Derivatives Containing Azepine and Acylhydrazone Moieties
por: Zhang, Jingjing, et al.
Publicado: (2022)

Synthesis, Antifungal, and Antibacterial Activities of Novel Benzoylurea Derivatives Containing a Pyrimidine Moiety
por: An, Jiansong, et al.
Publicado: (2023)

Synthesis and Antibacterial Activity of Novel Curcumin Derivatives Containing Heterocyclic Moiety
por: A. Hamed, Othman, et al.
Publicado: (2013)

Synthesis and Antitumor Activity of Novel Arylpiperazine Derivatives Containing the Saccharin Moiety
por: Chen, Hong, et al.
Publicado: (2017)

Design, Synthesis and Bioactivities of Novel Dichloro-Allyloxy-Phenol-Containing Pyrazole Oxime Derivatives
por: Dai, Hong, et al.
Publicado: (2015)

Design, Synthesis, and Bioactivity Evaluation of New Thiochromanone Derivatives Containing a Carboxamide Moiety
por: Xiao, Lingling, et al.
Publicado: (2021)

Microwave assisted synthesis, antifungal activity, DFT and SAR study of 1,2,4-triazolo[4,3-a]pyridine derivatives containing hydrazone moieties
por: Mu, Jin-Xia, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_5glacu51g81t8e34364mnmnqeg