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In Silico Docking and In Vitro Approaches towards BACE1 and Cholinesterases Inhibitory Effect of Citrus Flavanones

Alzheimer’s disease (AD) is the most prevalent neurodegenerative disease, distinctively characterized by senile plaques, neurofibrillary tangles, and synaptic loss, finally resulting in neuronal death. β-Site amyloid precursor protein (APP) cleaving enzyme 1 (BACE1) and cholinesterases have been ide...

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Detalles Bibliográficos
Autores principales: Lee, Seungeun, Youn, Kumju, Lim, GyuTae, Lee, Jinhyuk, Jun, Mira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100189/
https://www.ncbi.nlm.nih.gov/pubmed/29932100
http://dx.doi.org/10.3390/molecules23071509

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