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β-Phenylalanine Ester Synthesis from Stable β-Keto Ester Substrate Using Engineered ω-Transaminases

The successful synthesis of chiral amines from ketones using ω-transaminases has been shown in many cases in the last two decades. In contrast, the amination of β-keto acids is a special and relatively new challenge, as they decompose easily in aqueous solution. To avoid this, transamination of the...

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Detalles Bibliográficos
Autores principales:	Buß, Oliver, Voss, Moritz, Delavault, André, Gorenflo, Pascal, Syldatk, Christoph, Bornscheuer, Uwe, Rudat, Jens
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100204/ https://www.ncbi.nlm.nih.gov/pubmed/29783679 http://dx.doi.org/10.3390/molecules23051211

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