IL-2 Inhibition of Th17 Generation Rather Than Induction of Treg Cells Is Impaired in Primary Sjögren’s Syndrome Patients

OBJECTIVE: To investigate the role of IL-2 in the balance of Th17 and Tregs and elucidate the underlying mechanisms of enhanced Th17 differentiation in primary Sjögren’s syndrome (pSS) patients. METHODS: This study involved 31 pSS patients, 7 Sicca patients, and 31 healthy subjects. Th17 and Treg ce...

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Detalles Bibliográficos
Autores principales: Luo, Jing, Ming, Bingxia, Zhang, Cai, Deng, Xiaofei, Li, Pingfei, Wei, Zhengping, Xia, Yu, Jiang, Kan, Ye, Hong, Ma, Wanli, Liu, Zheng, Li, Huabin, Yang, Xiang-Ping, Dong, Lingli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100298/
https://www.ncbi.nlm.nih.gov/pubmed/30150979
http://dx.doi.org/10.3389/fimmu.2018.01755

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