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Polyamidoamine Dendrimers for Enhanced Solubility of Small Molecules and Other Desirable Properties for Site Specific Delivery: Insights from Experimental and Computational Studies
Clinical applications of many small molecules are limited due to poor solubility and lack of controlled release besides lack of other desirable properties. Experimental and computational studies have reported on the therapeutic potential of polyamidoamine (PAMAM) dendrimers as solubility enhancers i...
Autores principales: | Shadrack, Daniel M., Swai, Hulda S., Munissi, Joan J. E., Mubofu, Egid B., Nyandoro, Stephen S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100328/ https://www.ncbi.nlm.nih.gov/pubmed/29895742 http://dx.doi.org/10.3390/molecules23061419 |
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