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Simultaneous Determination of Decursin, Decursinol Angelate, Nodakenin, and Decursinol of Angelica gigas Nakai in Human Plasma by UHPLC-MS/MS: Application to Pharmacokinetic Study

Coumarins in Cham-dang-gwi, the dried root of Angelica gigas Nakai (AGN), possess pharmacological effects on anemia, pain, infection, and articular rheumatism. The AGN root containes decursin (D), decursinol angelate (DA), nodakenin, and decursinol (DOH), a major metabolite of D and DA. The aim of t...

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Detalles Bibliográficos
Autores principales: Kim, Sook-Jin, Ko, Se-Mi, Choi, Eun-Jeong, Ham, Seong-Ho, Kwon, Young-Dal, Lee, Yong-Bok, Cho, Hea-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100347/
https://www.ncbi.nlm.nih.gov/pubmed/29701699
http://dx.doi.org/10.3390/molecules23051019

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