Beckmann Rearrangement of Ketoxime Catalyzed by N-methyl-imidazolium Hydrosulfate

Beckmann rearrangement of ketoxime catalyzed by acidic ionic liquid-N-methyl-imidazolium hydrosulfate was studied. Rearrangement of benzophenone oxime gave the desirable product with 45% yield at 90 °C. When co-catalyst P(2)O(5) was added, the yield could be improved to 91%. The catalyst could be re...

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Detalles Bibliográficos
Autores principales: Hu, Hongyu, Cai, Xuting, Xu, Zhuying, Yan, Xiaoyang, Zhao, Shengxian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100402/
https://www.ncbi.nlm.nih.gov/pubmed/30021992
http://dx.doi.org/10.3390/molecules23071764
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author Hu, Hongyu
Cai, Xuting
Xu, Zhuying
Yan, Xiaoyang
Zhao, Shengxian
author_facet Hu, Hongyu
Cai, Xuting
Xu, Zhuying
Yan, Xiaoyang
Zhao, Shengxian
author_sort Hu, Hongyu
collection PubMed
description Beckmann rearrangement of ketoxime catalyzed by acidic ionic liquid-N-methyl-imidazolium hydrosulfate was studied. Rearrangement of benzophenone oxime gave the desirable product with 45% yield at 90 °C. When co-catalyst P(2)O(5) was added, the yield could be improved to 91%. The catalyst could be reused three cycles with the same efficiency. Finally, reactions of other ketoximes were also investigated.
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spelling pubmed-61004022018-11-13 Beckmann Rearrangement of Ketoxime Catalyzed by N-methyl-imidazolium Hydrosulfate Hu, Hongyu Cai, Xuting Xu, Zhuying Yan, Xiaoyang Zhao, Shengxian Molecules Article Beckmann rearrangement of ketoxime catalyzed by acidic ionic liquid-N-methyl-imidazolium hydrosulfate was studied. Rearrangement of benzophenone oxime gave the desirable product with 45% yield at 90 °C. When co-catalyst P(2)O(5) was added, the yield could be improved to 91%. The catalyst could be reused three cycles with the same efficiency. Finally, reactions of other ketoximes were also investigated. MDPI 2018-07-18 /pmc/articles/PMC6100402/ /pubmed/30021992 http://dx.doi.org/10.3390/molecules23071764 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Hu, Hongyu
Cai, Xuting
Xu, Zhuying
Yan, Xiaoyang
Zhao, Shengxian
Beckmann Rearrangement of Ketoxime Catalyzed by N-methyl-imidazolium Hydrosulfate
title Beckmann Rearrangement of Ketoxime Catalyzed by N-methyl-imidazolium Hydrosulfate
title_full Beckmann Rearrangement of Ketoxime Catalyzed by N-methyl-imidazolium Hydrosulfate
title_fullStr Beckmann Rearrangement of Ketoxime Catalyzed by N-methyl-imidazolium Hydrosulfate
title_full_unstemmed Beckmann Rearrangement of Ketoxime Catalyzed by N-methyl-imidazolium Hydrosulfate
title_short Beckmann Rearrangement of Ketoxime Catalyzed by N-methyl-imidazolium Hydrosulfate
title_sort beckmann rearrangement of ketoxime catalyzed by n-methyl-imidazolium hydrosulfate
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100402/
https://www.ncbi.nlm.nih.gov/pubmed/30021992
http://dx.doi.org/10.3390/molecules23071764
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