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General Method for the Synthesis of (−)-Conduritol C and Analogs from Chiral Cyclohexadienediol Scaffolds

An efficient and facile general method for the synthesis of conduritol C analogs, taking advantage of an enantioselective biocatalysis process of monosubstituted benzenes, is described. The absolute stereochemical patterns of the target molecules (−)-conduritol C, (−)-bromo-conduritol C, and (−)-met...

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Detalles Bibliográficos
Autores principales: Tibhe, Gaurao D., Macías, Mario A., Schapiro, Valeria, Suescun, Leopoldo, Pandolfi, Enrique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100410/
https://www.ncbi.nlm.nih.gov/pubmed/29986401
http://dx.doi.org/10.3390/molecules23071653