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In Silico Screening of Isocitrate Lyase for Novel Anti-Buruli Ulcer Natural Products Originating from Africa

Buruli ulcer (BU) is caused by Mycobacterium ulcerans and is predominant in both tropical and subtropical regions. The neglected debilitating disease is characterized by chronic necrotizing skin lesions attributed to a mycolactone, which is a macrolide toxin secreted by M. ulcerans. The preferred tr...

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Detalles Bibliográficos
Autores principales: Kwofie, Samuel K., Dankwa, Bismark, Odame, Emmanuel A., Agamah, Francis E., Doe, Lady P. A., Teye, Joshua, Agyapong, Odame, Miller, Whelton A., Mosi, Lydia, Wilson, Michael D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100440/
https://www.ncbi.nlm.nih.gov/pubmed/29954088
http://dx.doi.org/10.3390/molecules23071550