Secondary Metabolites from the Root Rot Biocontrol Fungus Phlebiopsis gigantea

Three cyclopentanoids (phlebiopsin A–C), one glycosylated p-terphenyl (methyl-terfestatin A), and o-orsellinaldehyde were isolated from the biocontrol fungus Phlebiopsis gigantea, and their structures were elucidated by 1D and 2D NMR spectroscopic analysis, as well as by LC-HRMS. The biological acti...

Descripción completa

Detalles Bibliográficos
Autores principales: Kälvö, David, Menkis, Audrius, Broberg, Anders
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100525/
https://www.ncbi.nlm.nih.gov/pubmed/29895730
http://dx.doi.org/10.3390/molecules23061417
Descripción
Sumario:Three cyclopentanoids (phlebiopsin A–C), one glycosylated p-terphenyl (methyl-terfestatin A), and o-orsellinaldehyde were isolated from the biocontrol fungus Phlebiopsis gigantea, and their structures were elucidated by 1D and 2D NMR spectroscopic analysis, as well as by LC-HRMS. The biological activity of the compounds against the root rot fungus Heterobasidion occidentale, as well as against Fusarium oxysporum and Penicillium canescens, was also investigated, but only o-orsellinaldehyde was found to have any antifungal activity in the concentration range tested.

Ejemplares similares