Secondary Metabolites from the Root Rot Biocontrol Fungus Phlebiopsis gigantea

Three cyclopentanoids (phlebiopsin A–C), one glycosylated p-terphenyl (methyl-terfestatin A), and o-orsellinaldehyde were isolated from the biocontrol fungus Phlebiopsis gigantea, and their structures were elucidated by 1D and 2D NMR spectroscopic analysis, as well as by LC-HRMS. The biological acti...

Descripción completa

Detalles Bibliográficos
Autores principales: Kälvö, David, Menkis, Audrius, Broberg, Anders
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100525/
https://www.ncbi.nlm.nih.gov/pubmed/29895730
http://dx.doi.org/10.3390/molecules23061417
_version_ 1783348894667636736
author Kälvö, David
Menkis, Audrius
Broberg, Anders
author_facet Kälvö, David
Menkis, Audrius
Broberg, Anders
author_sort Kälvö, David
collection PubMed
description Three cyclopentanoids (phlebiopsin A–C), one glycosylated p-terphenyl (methyl-terfestatin A), and o-orsellinaldehyde were isolated from the biocontrol fungus Phlebiopsis gigantea, and their structures were elucidated by 1D and 2D NMR spectroscopic analysis, as well as by LC-HRMS. The biological activity of the compounds against the root rot fungus Heterobasidion occidentale, as well as against Fusarium oxysporum and Penicillium canescens, was also investigated, but only o-orsellinaldehyde was found to have any antifungal activity in the concentration range tested.
format Online
Article
Text
id pubmed-6100525
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-61005252018-11-13 Secondary Metabolites from the Root Rot Biocontrol Fungus Phlebiopsis gigantea Kälvö, David Menkis, Audrius Broberg, Anders Molecules Article Three cyclopentanoids (phlebiopsin A–C), one glycosylated p-terphenyl (methyl-terfestatin A), and o-orsellinaldehyde were isolated from the biocontrol fungus Phlebiopsis gigantea, and their structures were elucidated by 1D and 2D NMR spectroscopic analysis, as well as by LC-HRMS. The biological activity of the compounds against the root rot fungus Heterobasidion occidentale, as well as against Fusarium oxysporum and Penicillium canescens, was also investigated, but only o-orsellinaldehyde was found to have any antifungal activity in the concentration range tested. MDPI 2018-06-12 /pmc/articles/PMC6100525/ /pubmed/29895730 http://dx.doi.org/10.3390/molecules23061417 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Kälvö, David
Menkis, Audrius
Broberg, Anders
Secondary Metabolites from the Root Rot Biocontrol Fungus Phlebiopsis gigantea
title Secondary Metabolites from the Root Rot Biocontrol Fungus Phlebiopsis gigantea
title_full Secondary Metabolites from the Root Rot Biocontrol Fungus Phlebiopsis gigantea
title_fullStr Secondary Metabolites from the Root Rot Biocontrol Fungus Phlebiopsis gigantea
title_full_unstemmed Secondary Metabolites from the Root Rot Biocontrol Fungus Phlebiopsis gigantea
title_short Secondary Metabolites from the Root Rot Biocontrol Fungus Phlebiopsis gigantea
title_sort secondary metabolites from the root rot biocontrol fungus phlebiopsis gigantea
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100525/
https://www.ncbi.nlm.nih.gov/pubmed/29895730
http://dx.doi.org/10.3390/molecules23061417
work_keys_str_mv AT kalvodavid secondarymetabolitesfromtherootrotbiocontrolfungusphlebiopsisgigantea
AT menkisaudrius secondarymetabolitesfromtherootrotbiocontrolfungusphlebiopsisgigantea
AT broberganders secondarymetabolitesfromtherootrotbiocontrolfungusphlebiopsisgigantea

Ejemplares similares