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Identification of Nutritional Components in Black Sesame Determined by Widely Targeted Metabolomics and Traditional Chinese Medicines

Chemical composition of secondary metabolites is of great importance for quality control of agricultural products. Black sesame seeds are significantly more expensive than white sesame seeds, because it is thought that black sesame seeds are more beneficial to human health than white sesame seeds. H...

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Detalles Bibliográficos
Autores principales: Wang, Dandan, Zhang, Liangxiao, Huang, Xiaorong, Wang, Xiao, Yang, Ruinan, Mao, Jin, Wang, Xuefang, Wang, Xiupin, Zhang, Qi, Li, Peiwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100530/
https://www.ncbi.nlm.nih.gov/pubmed/29762486
http://dx.doi.org/10.3390/molecules23051180
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author Wang, Dandan
Zhang, Liangxiao
Huang, Xiaorong
Wang, Xiao
Yang, Ruinan
Mao, Jin
Wang, Xuefang
Wang, Xiupin
Zhang, Qi
Li, Peiwu
author_facet Wang, Dandan
Zhang, Liangxiao
Huang, Xiaorong
Wang, Xiao
Yang, Ruinan
Mao, Jin
Wang, Xuefang
Wang, Xiupin
Zhang, Qi
Li, Peiwu
author_sort Wang, Dandan
collection PubMed
description Chemical composition of secondary metabolites is of great importance for quality control of agricultural products. Black sesame seeds are significantly more expensive than white sesame seeds, because it is thought that black sesame seeds are more beneficial to human health than white sesame seeds. However, the differences in nutrient composition between black sesame seeds and white sesame seeds are still unknown. The current study examined the levels of different metabolites in black and white sesame seeds via the use of a novel metabolomics strategy. Using widely targeted metabolomics data, we obtained the structure and content of 557 metabolites, out of which 217 metabolites were identified, and discovered 30 metabolic pathways activated by the secondary metabolites in both black and white sesame seeds. Our results demonstrated that the main pathways that were differentially activated included: phenylpropanoid biosynthesis, tyrosine metabolism, and riboflavin metabolism. More importantly, the biomarkers that were significantly different between black seeds and white sesame seeds are highly related to the functions recorded in traditional Chinese medicine. The results of this study may serve as a new theoretical reference for breeding experts to promote the genetic improvement of sesame seeds, and therefore the cultivation of higher quality sesame varieties.
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spelling pubmed-61005302018-11-13 Identification of Nutritional Components in Black Sesame Determined by Widely Targeted Metabolomics and Traditional Chinese Medicines Wang, Dandan Zhang, Liangxiao Huang, Xiaorong Wang, Xiao Yang, Ruinan Mao, Jin Wang, Xuefang Wang, Xiupin Zhang, Qi Li, Peiwu Molecules Article Chemical composition of secondary metabolites is of great importance for quality control of agricultural products. Black sesame seeds are significantly more expensive than white sesame seeds, because it is thought that black sesame seeds are more beneficial to human health than white sesame seeds. However, the differences in nutrient composition between black sesame seeds and white sesame seeds are still unknown. The current study examined the levels of different metabolites in black and white sesame seeds via the use of a novel metabolomics strategy. Using widely targeted metabolomics data, we obtained the structure and content of 557 metabolites, out of which 217 metabolites were identified, and discovered 30 metabolic pathways activated by the secondary metabolites in both black and white sesame seeds. Our results demonstrated that the main pathways that were differentially activated included: phenylpropanoid biosynthesis, tyrosine metabolism, and riboflavin metabolism. More importantly, the biomarkers that were significantly different between black seeds and white sesame seeds are highly related to the functions recorded in traditional Chinese medicine. The results of this study may serve as a new theoretical reference for breeding experts to promote the genetic improvement of sesame seeds, and therefore the cultivation of higher quality sesame varieties. MDPI 2018-05-15 /pmc/articles/PMC6100530/ /pubmed/29762486 http://dx.doi.org/10.3390/molecules23051180 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Wang, Dandan
Zhang, Liangxiao
Huang, Xiaorong
Wang, Xiao
Yang, Ruinan
Mao, Jin
Wang, Xuefang
Wang, Xiupin
Zhang, Qi
Li, Peiwu
Identification of Nutritional Components in Black Sesame Determined by Widely Targeted Metabolomics and Traditional Chinese Medicines
title Identification of Nutritional Components in Black Sesame Determined by Widely Targeted Metabolomics and Traditional Chinese Medicines
title_full Identification of Nutritional Components in Black Sesame Determined by Widely Targeted Metabolomics and Traditional Chinese Medicines
title_fullStr Identification of Nutritional Components in Black Sesame Determined by Widely Targeted Metabolomics and Traditional Chinese Medicines
title_full_unstemmed Identification of Nutritional Components in Black Sesame Determined by Widely Targeted Metabolomics and Traditional Chinese Medicines
title_short Identification of Nutritional Components in Black Sesame Determined by Widely Targeted Metabolomics and Traditional Chinese Medicines
title_sort identification of nutritional components in black sesame determined by widely targeted metabolomics and traditional chinese medicines
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100530/
https://www.ncbi.nlm.nih.gov/pubmed/29762486
http://dx.doi.org/10.3390/molecules23051180
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