Efficacy of Prosopilosidine from Prosopis glandulosa var. glandulosa against Cryptococcus neoformans Infection in a Murine Model

In this study, 2,3-dihydro-1H-indolizinium alkaloid-prosopilosidine (PPD), that was isolated from Prosopis glandulosa, was evaluated against C. neoformans in a murine model of cryptococcosis. In vitro and in vivo toxicity of indolizidines were also evaluated. Mice were infected via the tail vein wit...

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Detalles Bibliográficos
Autores principales: Ashfaq, Mohammad K., Abdel-Bakky, Mohamed Sadek, Tahir Maqbool, Mir, Samoylenko, Volodymyr, Abdur Rahman, Aziz, Muhammad, Ilias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100544/
https://www.ncbi.nlm.nih.gov/pubmed/29996473
http://dx.doi.org/10.3390/molecules23071674

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