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Preparation, Characterization, Pharmacokinetics and Biodistribution of Baicalin-Loaded Liposome on Cerebral Ischemia-Reperfusion after i.v. Administration in Rats

The dry root of Scutellaria baicalensis, has traditionally been applied in the treatment of cerebral ischemia in Chinese clinics. Baicalin (BA) is considered the key ingredient in it for the brain protection effects. The bioavailability of BA is very low because of its poor lipid and water solubilit...

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Detalles Bibliográficos
Autores principales: Li, Nan, Feng, Lingling, Tan, Yujun, Xiang, Yan, Zhang, Ruoqi, Yang, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100585/
https://www.ncbi.nlm.nih.gov/pubmed/30018228
http://dx.doi.org/10.3390/molecules23071747