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Preparation, Characterization, Pharmacokinetics and Biodistribution of Baicalin-Loaded Liposome on Cerebral Ischemia-Reperfusion after i.v. Administration in Rats
The dry root of Scutellaria baicalensis, has traditionally been applied in the treatment of cerebral ischemia in Chinese clinics. Baicalin (BA) is considered the key ingredient in it for the brain protection effects. The bioavailability of BA is very low because of its poor lipid and water solubilit...
Autores principales: | Li, Nan, Feng, Lingling, Tan, Yujun, Xiang, Yan, Zhang, Ruoqi, Yang, Ming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100585/ https://www.ncbi.nlm.nih.gov/pubmed/30018228 http://dx.doi.org/10.3390/molecules23071747 |
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