Ball Milling Promoted N-Heterocycles Synthesis

In the last years, numerous protocols have been published using ball milling for organic synthesis. Compared to other methods such as microwave or ultrasound irradiation and ionic liquids, ball mill chemistry is an economical, and ecofriendly method in organic synthesis that is rather underrepresent...

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Detalles Bibliográficos
Autores principales: El-Sayed, Taghreed H., Aboelnaga, Asmaa, El-Atawy, Mohamed A., Hagar, Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100593/
https://www.ncbi.nlm.nih.gov/pubmed/29867039
http://dx.doi.org/10.3390/molecules23061348
Descripción
Sumario:In the last years, numerous protocols have been published using ball milling for organic synthesis. Compared to other methods such as microwave or ultrasound irradiation and ionic liquids, ball mill chemistry is an economical, and ecofriendly method in organic synthesis that is rather underrepresented in the knowledge of organic chemists. The aim of this review is to explore the advantages of the application of ball milling in synthesis of N-heterocyclic compounds.

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