Cargando…

Protective Mechanism of Sulforaphane on Cadmium-Induced Sertoli Cell Injury in Mice Testis via Nrf2/ARE Signaling Pathway

The present study evaluated the mechanism underlying the protective effect of sulforaphane (SFN) on cadmium (Cd)-induced Sertoli cell (TM4 cells) injury in mice. The apoptosis rate of cells in each group was detected by flow cytometry. It was determined the effect of SFN on the expression of downstr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, Shu-Hua, Yu, Li-Hui, Li, Lin, Guo, Yang, Zhang, Yi, Long, Miao, Li, Peng, He, Jian-Bin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100605/ https://www.ncbi.nlm.nih.gov/pubmed/30029485 http://dx.doi.org/10.3390/molecules23071774

Ejemplares similares

Sulforaphane Protect Against Cadmium-Induced Oxidative Damage in mouse Leydigs Cells by Activating Nrf2/ARE Signaling Pathway
por: Yang, Shu-Hua, et al.
Publicado: (2019)

Sulforaphane Prevents Testicular Damage in Kunming Mice Exposed to Cadmium via Activation of Nrf2/ARE Signaling Pathways
por: Yang, Shu-Hua, et al.
Publicado: (2016)

Kindlin-2 in Sertoli cells is essential for testis development and male fertility in mice
por: Chi, Xiaochun, et al.
Publicado: (2021)

Protective mechanism of sulforaphane in Nrf2 and anti-lung injury in ARDS rabbits
por: Sun, Zongjian, et al.
Publicado: (2018)

Sulforaphane Protects against Cardiovascular Disease via Nrf2 Activation
por: Bai, Yang, et al.
Publicado: (2015)

Sulforaphane Protects Pancreatic Acinar Cell Injury by Modulating Nrf2-Mediated Oxidative Stress and NLRP3 Inflammatory Pathway
por: Dong, Zhaojun, et al.
Publicado: (2016)

Protective effects of sulforaphane on di-n-butylphthalate-induced testicular oxidative stress injury in male mice offsprings via activating Nrf2/ARE pathway
por: Qin, Zhiqiang, et al.
Publicado: (2017)

Sertoli Cells Are Susceptible to ZIKV Infection in Mouse Testis
por: Sheng, Zi-Yang, et al.
Publicado: (2017)

Protective effects of sulforaphane on diabetic retinopathy: activation of the Nrf2 pathway and inhibition of NLRP3 inflammasome formation
por: Li, Sheng, et al.
Publicado: (2019)

Factors affecting Sertoli cell function in the testis.
por: Tindall, D J, et al.
Publicado: (1981)

Sulforaphane protects against rotenone-induced neurotoxicity in vivo: Involvement of the mTOR, Nrf2, and autophagy pathways
por: Zhou, Qian, et al.
Publicado: (2016)

The sclerosing sertoli cell tumor of the testis: a case report
por: Tang, Xueyao, et al.
Publicado: (2023)

Sulforaphane Ameliorates Limb Ischemia/Reperfusion-Induced Muscular Injury in Mice by Inhibiting Pyroptosis and Autophagy via the Nrf2-ARE Pathway
por: Sun, Huanhuan, et al.
Publicado: (2022)

Zinc and low-dose of cadmium protect sertoli cells against toxic-dose of cadmium: The role of metallothionein
por: Kheradmand, Fatemeh, et al.
Publicado: (2013)

Sulforaphane increases Nrf2 expression and protects alveolar epithelial cells against injury caused by cigarette smoke extract
por: Jiao, Zongxian, et al.
Publicado: (2017)

Large cell calcifying Sertoli cell tumor of the testis
por: Al-Maghrabi, Jaudah A., et al.
Publicado: (2005)

Enrico Sertoli and the supporting cells of the testis “Morphology is function”
por: Patriarca, C., et al.
Publicado: (2019)

Effective isolation of Sertoli cells from New Zealand rabbit testis
por: Zhu, Wen-Qian, et al.
Publicado: (2021)

Ldha-Dependent Metabolic Programs in Sertoli Cells Regulate Spermiogenesis in Mouse Testis
por: Zhang, Xiao-Na, et al.
Publicado: (2022)

Prevention of Diabetic Nephropathy by Sulforaphane: Possible Role of Nrf2 Upregulation and Activation
por: Cui, Wenpeng, et al.
Publicado: (2012)

KEAP1 and done? Targeting the NRF2 pathway with sulforaphane
por: Dinkova-Kostova, Albena T., et al.
Publicado: (2017)

Sulforaphane Protects Rodent Retinas against Ischemia-Reperfusion Injury through the Activation of the Nrf2/HO-1 Antioxidant Pathway
por: Pan, Hong, et al.
Publicado: (2014)

PA1 participates in the maintenance of blood–testis barrier integrity via cooperation with JUN in the Sertoli cells of mice
por: Liu, Bo, et al.
Publicado: (2022)

Nrf2 expression and function, but not MT expression, is indispensable for sulforaphane-mediated protection against intermittent hypoxia-induced cardiomyopathy in mice
por: Zhou, Shanshan, et al.
Publicado: (2018)

The sclerosing Sertoli cell tumor of the testis is an extremely rare entity
por: Gomha, Faaz Salah, et al.
Publicado: (2020)

Activin A and Sertoli Cells: Key to Fetal Testis Steroidogenesis
por: O’Donnell, Liza, et al.
Publicado: (2022)

Zinc restores functionality in porcine prepubertal Sertoli cells exposed to subtoxic cadmium concentration via regulating the Nrf2 signaling pathway
por: Mancuso, Francesca, et al.
Publicado: (2023)

Toxicological Effects of Cadmium on Mammalian Testis
por: Zhu, Qiqi, et al.
Publicado: (2020)

An overview of a Sertoli cell transplantation model to study testis morphogenesis and the role of the Sertoli cells in immune privilege
por: Kaur, Gurvinder, et al.
Publicado: (2017)

Identification of Sertoli cell-specific transcripts in the mouse testis and the role of FSH and androgen in the control of Sertoli cell activity
por: Soffientini, U., et al.
Publicado: (2017)

Protective effects of sulforaphane and aerobic exercise on acute alcoholic hepatic injury in mice
por: Wang, Juan, et al.
Publicado: (2020)

Sulforaphane Does Not Protect Right Ventricular Systolic and Diastolic Functions in Nrf2 Knockout Pulmonary Artery Hypertension Mice
por: Zhang, Guangyan, et al.
Publicado: (2022)

Sulforaphane protects rabbit corneas against oxidative stress injury in keratoconus through activation of the Nrf-2/HO-1 antioxidant pathway
por: Liu, Ruixing, et al.
Publicado: (2018)

Astaxanthin Protects OTA-Induced Lung Injury in Mice through the Nrf2/NF-κB Pathway
por: Xu, Weixiang, et al.
Publicado: (2019)

Anticancer Activity of Sulforaphane: The Epigenetic Mechanisms and the Nrf2 Signaling Pathway
por: Su, Xuling, et al.
Publicado: (2018)

Varicocele-Caused Progressive Damage in Bilateral Testis and Sertoli Cell-Only Syndrome in Homolateral Testis in Rats
por: Liu, Jianjun, et al.
Publicado: (2014)

Sulforaphane alleviates lung ischemia‑reperfusion injury through activating Nrf‑2/HO‑1 signaling
por: Zhang, Liang, et al.
Publicado: (2023)

Sulforaphane inhibits angiotensin II-induced cardiomyocyte apoptosis by acetylation modification of Nrf2
por: Wang, Huanhuan, et al.
Publicado: (2022)

The Protective Effect of Sulforaphane against Oxidative Stress through Activation of NRF2/ARE Pathway in Human Granulosa Cells
por: Esfandyari, Sahar, et al.
Publicado: (2021)

Ferroptosis is essential for diabetic cardiomyopathy and is prevented by sulforaphane via AMPK/NRF2 pathways
por: Wang, Xiang, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_c8ksqr7i435pcjqruspjvpe1tm