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Characterization of kinase gene expression and splicing profile in prostate cancer with RNA-Seq data

BACKGROUND: Alternative splicing is a ubiquitous post-transcriptional regulation mechanism in most eukaryotic genes. Aberrant splicing isoforms and abnormal isoform ratios can contribute to cancer development. Kinase genes are key regulators of multiple cellular processes. Many kinases are found to...

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Detalles Bibliográficos
Autores principales: Feng, Huijuan, Li, Tingting, Zhang, Xuegong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6101066/
https://www.ncbi.nlm.nih.gov/pubmed/30367578
http://dx.doi.org/10.1186/s12864-018-4925-1