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Characterization of kinase gene expression and splicing profile in prostate cancer with RNA-Seq data
BACKGROUND: Alternative splicing is a ubiquitous post-transcriptional regulation mechanism in most eukaryotic genes. Aberrant splicing isoforms and abnormal isoform ratios can contribute to cancer development. Kinase genes are key regulators of multiple cellular processes. Many kinases are found to...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6101066/ https://www.ncbi.nlm.nih.gov/pubmed/30367578 http://dx.doi.org/10.1186/s12864-018-4925-1 |