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A graph-based approach for proteoform identification and quantification using top-down homogeneous multiplexed tandem mass spectra
BACKGROUND: Top-down homogeneous multiplexed tandem mass (HomMTM) spectra are generated from modified proteoforms of the same protein with different post-translational modification patterns. They are frequently observed in the analysis of ultramodified proteins, some proteoforms of which have simila...
Autores principales: | Zhu, Kaiyuan, Liu, Xiaowen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6101081/ https://www.ncbi.nlm.nih.gov/pubmed/30367573 http://dx.doi.org/10.1186/s12859-018-2273-4 |
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