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A graph-based approach for proteoform identification and quantification using top-down homogeneous multiplexed tandem mass spectra

BACKGROUND: Top-down homogeneous multiplexed tandem mass (HomMTM) spectra are generated from modified proteoforms of the same protein with different post-translational modification patterns. They are frequently observed in the analysis of ultramodified proteins, some proteoforms of which have simila...

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Detalles Bibliográficos
Autores principales: Zhu, Kaiyuan, Liu, Xiaowen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6101081/
https://www.ncbi.nlm.nih.gov/pubmed/30367573
http://dx.doi.org/10.1186/s12859-018-2273-4

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