Chromatin-associated APC regulates gene expression in collaboration with canonical WNT signaling and AP-1

Mutation of the APC gene occurs in a high percentage of colorectal tumors and is a central event driving tumor initiation in the large intestine. The APC protein performs multiple tumor suppressor functions including negative regulation of the canonical WNT signaling pathway by both cytoplasmic and...

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Detalles Bibliográficos
Autores principales: Hankey, William, Chen, Zhong, Bergman, Maxwell J., Fernandez, Max O., Hancioglu, Baris, Lan, Xun, Jegga, Anil G., Zhang, Jie, Jin, Victor X., Aronow, Bruce J., Wang, Qianben, Groden, Joanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6101278/
https://www.ncbi.nlm.nih.gov/pubmed/30131849
http://dx.doi.org/10.18632/oncotarget.25781

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