CAPN1 is a novel binding partner and regulator of the tumor suppressor NF1 in melanoma

Neurofibromin 1 (NF1), a tumor suppressor that negatively regulates RAS through its GTPase activity, is highly mutated in various types of sporadic human cancers, including melanoma. However, the binding partners of NF1 and the pathways in which it is involved in melanoma have not been characterized...

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Detalles Bibliográficos
Autores principales: Alon, Michal, Arafeh, Rand, Lee, Joo Sang, Madan, Sanna, Kalaora, Shelly, Nagler, Adi, Abgarian, Tereza, Greenberg, Polina, Ruppin, Eytan, Samuels, Yardena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6101293/
https://www.ncbi.nlm.nih.gov/pubmed/30131853
http://dx.doi.org/10.18632/oncotarget.25805

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6101293/
https://www.ncbi.nlm.nih.gov/pubmed/30131853
http://dx.doi.org/10.18632/oncotarget.25805

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