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Naturally-occurring canine invasive urothelial carcinoma harbors luminal and basal transcriptional subtypes found in human muscle invasive bladder cancer

There is growing evidence that molecular subtypes (e.g. luminal and basal subtypes) affect the prognosis and treatment response in patients with muscle invasive urinary bladder cancer (invasive urothelial carcinoma, iUC). Modeling these subtypes in pre-clinical animal studies is essential, but it is...

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Detalles Bibliográficos
Autores principales: Dhawan, Deepika, Hahn, Noah M., Ramos-Vara, José A., Knapp, Deborah W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6101404/
https://www.ncbi.nlm.nih.gov/pubmed/30089113
http://dx.doi.org/10.1371/journal.pgen.1007571