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Regulation of miR-34b/c-targeted gene expression program by SUMOylation
The miR-34 family of microRNAs suppresses the expression of proteins involved in pluripotency and oncogenesis. miR-34 expression is frequently reduced in cancers; however, the regulation of their expression is not well understood. We used genome-wide miRNA profiling and mechanistic analysis to show...
Autores principales: | Li, Yi-Jia, Du, Li, Aldana-Masangkay, Grace, Wang, Xiuli, Urak, Ryan, Forman, Stephen J, Rosen, Steven T, Chen, Yuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6101486/ https://www.ncbi.nlm.nih.gov/pubmed/29893976 http://dx.doi.org/10.1093/nar/gky484 |
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