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Urban Birth, Urban Living, and Work Migrancy: Differential Effects on Psychotic Experiences Among Young Chinese Men

BACKGROUND: Urban birth and urban living are associated with increased risk of schizophrenia but less is known about effects on more common psychotic experiences (PEs). China has undergone the most rapid urbanization of any country which may have affected the population-level expression of psychosis...

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Autores principales: Coid, Jeremy W, Hu, Junmei, Kallis, Constantinos, Ping, Yuan, Zhang, Juying, Hu, Yueying, Zhang, Tianqiang, Gonzalez, Rafael, Ullrich, Simone, Jones, Peter B, Kirkbride, James B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6101522/
https://www.ncbi.nlm.nih.gov/pubmed/29301013
http://dx.doi.org/10.1093/schbul/sbx152
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author Coid, Jeremy W
Hu, Junmei
Kallis, Constantinos
Ping, Yuan
Zhang, Juying
Hu, Yueying
Zhang, Tianqiang
Gonzalez, Rafael
Ullrich, Simone
Jones, Peter B
Kirkbride, James B
author_facet Coid, Jeremy W
Hu, Junmei
Kallis, Constantinos
Ping, Yuan
Zhang, Juying
Hu, Yueying
Zhang, Tianqiang
Gonzalez, Rafael
Ullrich, Simone
Jones, Peter B
Kirkbride, James B
author_sort Coid, Jeremy W
collection PubMed
description BACKGROUND: Urban birth and urban living are associated with increased risk of schizophrenia but less is known about effects on more common psychotic experiences (PEs). China has undergone the most rapid urbanization of any country which may have affected the population-level expression of psychosis. We therefore investigated effects of urbanicity, work migrancy, and residential stability on prevalence and severity of PEs. METHODS: Population-based, 2-wave household survey of psychiatric morbidity and health-related behavior among 4132 men, 18–34 years of age living in urban and rural Greater Chengdu, Sichuan Province, China. PEs were measured using the Psychosis Screening Questionnaire. RESULTS: 1261 (31%) of young men experienced at least 1 PE. Lower levels of PEs were not associated with urbanicity, work migrancy or residential stability. Urban birth was associated with reporting 3 or more PEs (OR: 1.63; 95% CI: 1.25–2.11), after multivariable adjustment, with further evidence (P = .01) this effect was restricted to those currently living in urban environments (OR: 1.78; 95% CI: 1.16–2.72). Men experiencing a maximum of 5 PEs were over 8 times more likely to have been born in an urban area (adjusted odds ratio [AOR] 8.81; 95% CI 1.50–51.79). CONCLUSIONS: Men in Chengdu, China, experience a high prevalence of PEs. This may be explained by rapid urbanization and residential instability. Urban birth was specifically associated with high, but not lower, severity levels of PEs, particularly amongst those currently living in urban environments. This suggests that early and sustained environmental exposures may be associated with more severe phenotypes.
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spelling pubmed-61015222018-08-27 Urban Birth, Urban Living, and Work Migrancy: Differential Effects on Psychotic Experiences Among Young Chinese Men Coid, Jeremy W Hu, Junmei Kallis, Constantinos Ping, Yuan Zhang, Juying Hu, Yueying Zhang, Tianqiang Gonzalez, Rafael Ullrich, Simone Jones, Peter B Kirkbride, James B Schizophr Bull Regular Articles BACKGROUND: Urban birth and urban living are associated with increased risk of schizophrenia but less is known about effects on more common psychotic experiences (PEs). China has undergone the most rapid urbanization of any country which may have affected the population-level expression of psychosis. We therefore investigated effects of urbanicity, work migrancy, and residential stability on prevalence and severity of PEs. METHODS: Population-based, 2-wave household survey of psychiatric morbidity and health-related behavior among 4132 men, 18–34 years of age living in urban and rural Greater Chengdu, Sichuan Province, China. PEs were measured using the Psychosis Screening Questionnaire. RESULTS: 1261 (31%) of young men experienced at least 1 PE. Lower levels of PEs were not associated with urbanicity, work migrancy or residential stability. Urban birth was associated with reporting 3 or more PEs (OR: 1.63; 95% CI: 1.25–2.11), after multivariable adjustment, with further evidence (P = .01) this effect was restricted to those currently living in urban environments (OR: 1.78; 95% CI: 1.16–2.72). Men experiencing a maximum of 5 PEs were over 8 times more likely to have been born in an urban area (adjusted odds ratio [AOR] 8.81; 95% CI 1.50–51.79). CONCLUSIONS: Men in Chengdu, China, experience a high prevalence of PEs. This may be explained by rapid urbanization and residential instability. Urban birth was specifically associated with high, but not lower, severity levels of PEs, particularly amongst those currently living in urban environments. This suggests that early and sustained environmental exposures may be associated with more severe phenotypes. Oxford University Press 2018-08 2017-12-29 /pmc/articles/PMC6101522/ /pubmed/29301013 http://dx.doi.org/10.1093/schbul/sbx152 Text en © The Author(s) 2017. Published by Oxford University Press on behalf of the Maryland Psychiatric Research Center. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Regular Articles
Coid, Jeremy W
Hu, Junmei
Kallis, Constantinos
Ping, Yuan
Zhang, Juying
Hu, Yueying
Zhang, Tianqiang
Gonzalez, Rafael
Ullrich, Simone
Jones, Peter B
Kirkbride, James B
Urban Birth, Urban Living, and Work Migrancy: Differential Effects on Psychotic Experiences Among Young Chinese Men
title Urban Birth, Urban Living, and Work Migrancy: Differential Effects on Psychotic Experiences Among Young Chinese Men
title_full Urban Birth, Urban Living, and Work Migrancy: Differential Effects on Psychotic Experiences Among Young Chinese Men
title_fullStr Urban Birth, Urban Living, and Work Migrancy: Differential Effects on Psychotic Experiences Among Young Chinese Men
title_full_unstemmed Urban Birth, Urban Living, and Work Migrancy: Differential Effects on Psychotic Experiences Among Young Chinese Men
title_short Urban Birth, Urban Living, and Work Migrancy: Differential Effects on Psychotic Experiences Among Young Chinese Men
title_sort urban birth, urban living, and work migrancy: differential effects on psychotic experiences among young chinese men
topic Regular Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6101522/
https://www.ncbi.nlm.nih.gov/pubmed/29301013
http://dx.doi.org/10.1093/schbul/sbx152
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