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Bacillus subtilis RarA modulates replication restart

The ubiquitous RarA/Mgs1/WRNIP protein plays a crucial, but poorly understood role in genome maintenance. We show that Bacillus subtilis RarA, in the apo form, preferentially binds single-stranded (ss) over double-stranded (ds) DNA. SsbA bound to ssDNA loads RarA, and for such recruitment the amphip...

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Detalles Bibliográficos
Autores principales:	Carrasco, Begoña, Seco, Elena M, López-Sanz, María, Alonso, Juan C, Ayora, Silvia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2018
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6101539/ https://www.ncbi.nlm.nih.gov/pubmed/29947798 http://dx.doi.org/10.1093/nar/gky541

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