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The mitochondrial single-stranded DNA binding protein from S. cerevisiae, Rim1, does not form stable homo-tetramers and binds DNA as a dimer of dimers

Rim1 is the mitochondrial single-stranded DNA binding protein in Saccharomyces cerevisiae and functions to coordinate replication and maintenance of mtDNA. Rim1 can form homo-tetramers in solution and this species has been assumed to be solely responsible for ssDNA binding. We solved structures of t...

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Detalles Bibliográficos
Autores principales:	Singh, Saurabh P, Kukshal, Vandna, De Bona, Paolo, Antony, Edwin, Galletto, Roberto
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2018
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6101547/ https://www.ncbi.nlm.nih.gov/pubmed/29931186 http://dx.doi.org/10.1093/nar/gky530

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