DNA repair factor APLF acts as a H2A-H2B histone chaperone through binding its DNA interaction surface

Genome replication, transcription and repair require the assembly/disassembly of the nucleosome. Histone chaperones are regulators of this process by preventing formation of non-nucleosomal histone–DNA complexes. Aprataxin and polynucleotide kinase like factor (APLF) is a non-homologous end-joining...

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Detalles Bibliográficos
Autores principales: Corbeski, Ivan, Dolinar, Klemen, Wienk, Hans, Boelens, Rolf, van Ingen, Hugo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6101569/
https://www.ncbi.nlm.nih.gov/pubmed/29905837
http://dx.doi.org/10.1093/nar/gky507

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6101569/
https://www.ncbi.nlm.nih.gov/pubmed/29905837
http://dx.doi.org/10.1093/nar/gky507

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