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DNA repair factor APLF acts as a H2A-H2B histone chaperone through binding its DNA interaction surface
Genome replication, transcription and repair require the assembly/disassembly of the nucleosome. Histone chaperones are regulators of this process by preventing formation of non-nucleosomal histone–DNA complexes. Aprataxin and polynucleotide kinase like factor (APLF) is a non-homologous end-joining...
Autores principales: | Corbeski, Ivan, Dolinar, Klemen, Wienk, Hans, Boelens, Rolf, van Ingen, Hugo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6101569/ https://www.ncbi.nlm.nih.gov/pubmed/29905837 http://dx.doi.org/10.1093/nar/gky507 |
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