Acute Kidney Injury in a Patient on Tenofovir Alafenamide Fumarate After Initiation of Treatment for Hepatitis C Virus Infection

HIV treatment with tenofovir alafenamide fumarate (TAF) has decreased renal toxicity compared with tenofovir disoproxil fumarate in clinical trials. We report the case of a patient with HIV/HCV coinfection who was started on a TAF-based HIV regimen and developed acute kidney injury that worsened wit...

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Autores principales: Serota, David P, Franch, Harold A, Cartwright, Emily J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6101585/
https://www.ncbi.nlm.nih.gov/pubmed/30151414
http://dx.doi.org/10.1093/ofid/ofy189
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author Serota, David P
Franch, Harold A
Cartwright, Emily J
author_facet Serota, David P
Franch, Harold A
Cartwright, Emily J
author_sort Serota, David P
collection PubMed
description HIV treatment with tenofovir alafenamide fumarate (TAF) has decreased renal toxicity compared with tenofovir disoproxil fumarate in clinical trials. We report the case of a patient with HIV/HCV coinfection who was started on a TAF-based HIV regimen and developed acute kidney injury that worsened with the addition of sofosbuvir-ledipasvir.
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spelling pubmed-61015852018-08-27 Acute Kidney Injury in a Patient on Tenofovir Alafenamide Fumarate After Initiation of Treatment for Hepatitis C Virus Infection Serota, David P Franch, Harold A Cartwright, Emily J Open Forum Infect Dis Brief Report HIV treatment with tenofovir alafenamide fumarate (TAF) has decreased renal toxicity compared with tenofovir disoproxil fumarate in clinical trials. We report the case of a patient with HIV/HCV coinfection who was started on a TAF-based HIV regimen and developed acute kidney injury that worsened with the addition of sofosbuvir-ledipasvir. Oxford University Press 2018-07-30 /pmc/articles/PMC6101585/ /pubmed/30151414 http://dx.doi.org/10.1093/ofid/ofy189 Text en © The Author(s) 2018. Published by Oxford University Press on behalf of Infectious Diseases Society of America. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Brief Report
Serota, David P
Franch, Harold A
Cartwright, Emily J
Acute Kidney Injury in a Patient on Tenofovir Alafenamide Fumarate After Initiation of Treatment for Hepatitis C Virus Infection
title Acute Kidney Injury in a Patient on Tenofovir Alafenamide Fumarate After Initiation of Treatment for Hepatitis C Virus Infection
title_full Acute Kidney Injury in a Patient on Tenofovir Alafenamide Fumarate After Initiation of Treatment for Hepatitis C Virus Infection
title_fullStr Acute Kidney Injury in a Patient on Tenofovir Alafenamide Fumarate After Initiation of Treatment for Hepatitis C Virus Infection
title_full_unstemmed Acute Kidney Injury in a Patient on Tenofovir Alafenamide Fumarate After Initiation of Treatment for Hepatitis C Virus Infection
title_short Acute Kidney Injury in a Patient on Tenofovir Alafenamide Fumarate After Initiation of Treatment for Hepatitis C Virus Infection
title_sort acute kidney injury in a patient on tenofovir alafenamide fumarate after initiation of treatment for hepatitis c virus infection
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6101585/
https://www.ncbi.nlm.nih.gov/pubmed/30151414
http://dx.doi.org/10.1093/ofid/ofy189
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