Cetirizine-induced hepatotoxicity: case series and review of the literature

Drug-induced liver damage is a frequently encountered clinical table caused by many drugs. Cetirizine is a widely preferred and prescribed antihistaminic agent for allergic disorders due to its non-sedative properties. In view of the literature, we present four cases of hepatotoxicity due to cetiriz...

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Autores principales: Coskun, Adil, Yavasoglu, Irfan, Yasa, M Hadi, Culhaci, Nil, Yukselen, Vahit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6101603/
https://www.ncbi.nlm.nih.gov/pubmed/27576471
http://dx.doi.org/10.1093/gastro/gow025
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author Coskun, Adil
Yavasoglu, Irfan
Yasa, M Hadi
Culhaci, Nil
Yukselen, Vahit
author_facet Coskun, Adil
Yavasoglu, Irfan
Yasa, M Hadi
Culhaci, Nil
Yukselen, Vahit
author_sort Coskun, Adil
collection PubMed
description Drug-induced liver damage is a frequently encountered clinical table caused by many drugs. Cetirizine is a widely preferred and prescribed antihistaminic agent for allergic disorders due to its non-sedative properties. In view of the literature, we present four cases of hepatotoxicity due to cetirizine use. We conclude that in patients with high levels of liver enzymes of unknown origin, cetirizine as well as other hepatotoxic drugs should be reconsidered.
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spelling pubmed-61016032018-08-27 Cetirizine-induced hepatotoxicity: case series and review of the literature Coskun, Adil Yavasoglu, Irfan Yasa, M Hadi Culhaci, Nil Yukselen, Vahit Gastroenterol Rep (Oxf) Case Reports Drug-induced liver damage is a frequently encountered clinical table caused by many drugs. Cetirizine is a widely preferred and prescribed antihistaminic agent for allergic disorders due to its non-sedative properties. In view of the literature, we present four cases of hepatotoxicity due to cetirizine use. We conclude that in patients with high levels of liver enzymes of unknown origin, cetirizine as well as other hepatotoxic drugs should be reconsidered. Oxford University Press 2018-08 2016-08-27 /pmc/articles/PMC6101603/ /pubmed/27576471 http://dx.doi.org/10.1093/gastro/gow025 Text en © The Author(s) 2016. Published by Oxford University Press and Sixth Affiliated Hospital of Sun Yat-Sen University http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Case Reports
Coskun, Adil
Yavasoglu, Irfan
Yasa, M Hadi
Culhaci, Nil
Yukselen, Vahit
Cetirizine-induced hepatotoxicity: case series and review of the literature
title Cetirizine-induced hepatotoxicity: case series and review of the literature
title_full Cetirizine-induced hepatotoxicity: case series and review of the literature
title_fullStr Cetirizine-induced hepatotoxicity: case series and review of the literature
title_full_unstemmed Cetirizine-induced hepatotoxicity: case series and review of the literature
title_short Cetirizine-induced hepatotoxicity: case series and review of the literature
title_sort cetirizine-induced hepatotoxicity: case series and review of the literature
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6101603/
https://www.ncbi.nlm.nih.gov/pubmed/27576471
http://dx.doi.org/10.1093/gastro/gow025
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AT yasamhadi cetirizineinducedhepatotoxicitycaseseriesandreviewoftheliterature
AT culhacinil cetirizineinducedhepatotoxicitycaseseriesandreviewoftheliterature
AT yukselenvahit cetirizineinducedhepatotoxicitycaseseriesandreviewoftheliterature

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