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Analysis of Beta-cell Function Using Single-cell Resolution Calcium Imaging in Zebrafish Islets
Pancreatic beta-cells respond to increasing blood glucose concentrations by secreting the hormone insulin. The dysfunction of beta-cells leads to hyperglycemia and severe, life-threatening consequences. Understanding how the beta-cells operate under physiological conditions and what genetic and envi...
Autores principales: | Janjuha, Sharan, Pal Singh, Sumeet, Ninov, Nikolay |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MyJove Corporation
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6102039/ https://www.ncbi.nlm.nih.gov/pubmed/30035763 http://dx.doi.org/10.3791/57851 |
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