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Multi-scale, whole-system models of liver metabolic adaptation to fat and sugar in non-alcoholic fatty liver disease

Non-alcoholic fatty liver disease (NAFLD) is a serious public health issue associated with high fat, high sugar diets. However, the molecular mechanisms mediating NAFLD pathogenesis are only partially understood. Here we adopt an iterative multi-scale, systems biology approach coupled to in vitro ex...

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Detalles Bibliográficos
Autores principales:	Maldonado, Elaina M., Fisher, Ciarán P., Mazzatti, Dawn J., Barber, Amy L., Tindall, Marcus J., Plant, Nicholas J., Kierzek, Andrzej M., Moore, J. Bernadette
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6102210/ https://www.ncbi.nlm.nih.gov/pubmed/30131870 http://dx.doi.org/10.1038/s41540-018-0070-3

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