LTR retrotransposons transcribed in oocytes drive species-specific and heritable changes in DNA methylation

De novo DNA methylation (DNAme) during mouse oogenesis occurs within transcribed regions enriched for H3K36me3. As many oocyte transcripts originate in long terminal repeats (LTRs), which are heterogeneous even between closely related mammals, we examined whether species-specific LTR-initiated trans...

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Detalles Bibliográficos
Autores principales: Brind’Amour, Julie, Kobayashi, Hisato, Richard Albert, Julien, Shirane, Kenjiro, Sakashita, Akihiko, Kamio, Asuka, Bogutz, Aaron, Koike, Tasuku, Karimi, Mohammad M., Lefebvre, Louis, Kono, Tomohiro, Lorincz, Matthew C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6102241/
https://www.ncbi.nlm.nih.gov/pubmed/30127397
http://dx.doi.org/10.1038/s41467-018-05841-x

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