Intrathecal delivery of human ESC-derived mesenchymal stem cell spheres promotes recovery of a primate multiple sclerosis model

Nonhuman primate experimental autoimmune encephalomyelitis (EAE) is a valuable model for multiple sclerosis, an inflammatory demyelinating disease in the central nervous system (CNS). Human embryonic stem cell-derived mesenchymal stem cells (EMSC) are effective in treating murine EAE. Yet, it remain...

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Detalles Bibliográficos
Autores principales: Yan, Li, Jiang, Bin, Niu, Yuyu, Wang, Hongxuan, Li, Enqin, Yan, Yaping, Sun, Huiyan, Duan, Yanchao, Chang, Shaohui, Chen, Guokai, Ji, Weizhi, Xu, Ren-He, Si, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6102276/
https://www.ncbi.nlm.nih.gov/pubmed/30131877
http://dx.doi.org/10.1038/s41420-018-0091-0

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