Cigarette smoke exposure decreases CFLAR expression in the bronchial epithelium, augmenting susceptibility for lung epithelial cell death and DAMP release

Cigarette smoking is a major risk factor for the inflammatory disease, chronic obstructive pulmonary disease (COPD). The mechanism by which cigarette smoke (CS) induces chronic lung inflammation is still largely unknown. We hypothesize that immunogenic airway epithelial cell death is involved in the...

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Detalles Bibliográficos
Autores principales: Faiz, Alen, Heijink, Irene H., Vermeulen, Cornelis J., Guryev, Victor, van den Berge, Maarten, Nawijn, Martijn C., Pouwels, Simon D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6102306/
https://www.ncbi.nlm.nih.gov/pubmed/30127367
http://dx.doi.org/10.1038/s41598-018-30602-7

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