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Interlimb Generalization of Learned Bayesian Visuomotor Prior Occurs in Extrinsic Coordinates

Recent work suggests that the brain represents probability distributions and performs Bayesian integration during sensorimotor learning. However, our understanding of the neural representation of this learning remains limited. To begin to address this, we performed two experiments. In the first expe...

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Detalles Bibliográficos
Autores principales: Hewitson, Christopher L., Sowman, Paul F., Kaplan, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6102376/
https://www.ncbi.nlm.nih.gov/pubmed/30131969
http://dx.doi.org/10.1523/ENEURO.0183-18.2018
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author Hewitson, Christopher L.
Sowman, Paul F.
Kaplan, David M.
author_facet Hewitson, Christopher L.
Sowman, Paul F.
Kaplan, David M.
author_sort Hewitson, Christopher L.
collection PubMed
description Recent work suggests that the brain represents probability distributions and performs Bayesian integration during sensorimotor learning. However, our understanding of the neural representation of this learning remains limited. To begin to address this, we performed two experiments. In the first experiment, we replicated the key behavioral findings of Körding and Wolpert (2004), demonstrating that humans can perform in a Bayes-optimal manner by combining information about their own sensory uncertainty and a statistical distribution of lateral shifts encountered in a visuomotor adaptation task. In the second experiment, we extended these findings by testing whether visuomotor learning occurring during the same task generalizes from one limb to the other, and relatedly, whether this learning is represented in an extrinsic or intrinsic reference frame. We found that the learned mean of the distribution of visuomotor shifts generalizes to the opposite limb only when the perturbation is congruent in extrinsic coordinates, indicating that the underlying representation of learning acquired during training is available to the untrained limb and is coded in an extrinsic reference frame.
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spelling pubmed-61023762018-08-21 Interlimb Generalization of Learned Bayesian Visuomotor Prior Occurs in Extrinsic Coordinates Hewitson, Christopher L. Sowman, Paul F. Kaplan, David M. eNeuro Confirmation Recent work suggests that the brain represents probability distributions and performs Bayesian integration during sensorimotor learning. However, our understanding of the neural representation of this learning remains limited. To begin to address this, we performed two experiments. In the first experiment, we replicated the key behavioral findings of Körding and Wolpert (2004), demonstrating that humans can perform in a Bayes-optimal manner by combining information about their own sensory uncertainty and a statistical distribution of lateral shifts encountered in a visuomotor adaptation task. In the second experiment, we extended these findings by testing whether visuomotor learning occurring during the same task generalizes from one limb to the other, and relatedly, whether this learning is represented in an extrinsic or intrinsic reference frame. We found that the learned mean of the distribution of visuomotor shifts generalizes to the opposite limb only when the perturbation is congruent in extrinsic coordinates, indicating that the underlying representation of learning acquired during training is available to the untrained limb and is coded in an extrinsic reference frame. Society for Neuroscience 2018-08-08 /pmc/articles/PMC6102376/ /pubmed/30131969 http://dx.doi.org/10.1523/ENEURO.0183-18.2018 Text en Copyright © 2018 Hewitson et al. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.
spellingShingle Confirmation
Hewitson, Christopher L.
Sowman, Paul F.
Kaplan, David M.
Interlimb Generalization of Learned Bayesian Visuomotor Prior Occurs in Extrinsic Coordinates
title Interlimb Generalization of Learned Bayesian Visuomotor Prior Occurs in Extrinsic Coordinates
title_full Interlimb Generalization of Learned Bayesian Visuomotor Prior Occurs in Extrinsic Coordinates
title_fullStr Interlimb Generalization of Learned Bayesian Visuomotor Prior Occurs in Extrinsic Coordinates
title_full_unstemmed Interlimb Generalization of Learned Bayesian Visuomotor Prior Occurs in Extrinsic Coordinates
title_short Interlimb Generalization of Learned Bayesian Visuomotor Prior Occurs in Extrinsic Coordinates
title_sort interlimb generalization of learned bayesian visuomotor prior occurs in extrinsic coordinates
topic Confirmation
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6102376/
https://www.ncbi.nlm.nih.gov/pubmed/30131969
http://dx.doi.org/10.1523/ENEURO.0183-18.2018
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