Cargando…

Synthesis of New Glycosylated Flavonoids with Inhibitory Activity on Cell Growth

Natural flavonoids and xanthone glycosides display several biological activities, with the glycoside moiety playing an important role in the mechanism of action of these metabolites. Herein, to give further insights into the inhibitory activity on cell growth of these classes of compounds, the synth...

Descripción completa

Detalles Bibliográficos
Autores principales:	Neves, Ana R., Correia-da-Silva, Marta, Silva, Patrícia M. A., Ribeiro, Diana, Sousa, Emília, Bousbaa, Hassan, Pinto, Madalena
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6102538/ https://www.ncbi.nlm.nih.gov/pubmed/29734739 http://dx.doi.org/10.3390/molecules23051093

Ejemplares similares

Discovery of a New Xanthone against Glioma: Synthesis and Development of (Pro)liposome Formulations
por: Alves, Ana, et al.
Publicado: (2019)

Strategies to Overcome Heparins’ Low Oral Bioavailability
por: Neves, Ana Rita, et al.
Publicado: (2016)

New Alkoxy Flavone Derivatives Targeting Caspases: Synthesis and Antitumor Activity Evaluation
por: Moreira, Joana, et al.
Publicado: (2018)

Recent Advances in Bioactive Flavonoid Hybrids Linked by 1,2,3-Triazole Ring Obtained by Click Chemistry
por: Pereira, Daniela, et al.
Publicado: (2021)

Flavonoid Glycosides with a Triazole Moiety for Marine Antifouling Applications: Synthesis and Biological Activity Evaluation
por: Pereira, Daniela, et al.
Publicado: (2020)

Discovery of a New Chalcone-Trimethoxycinnamide Hybrid with Antimitotic Effect: Design, Synthesis, and Structure—Activity Relationship Studies
por: Moreira, Joana, et al.
Publicado: (2023)

Therapeutic Potential of Glycosyl Flavonoids as Anti-Coronaviral Agents
por: Godinho, Patrícia I. C., et al.
Publicado: (2021)

Tetracyclic Thioxanthene Derivatives: Studies on Fluorescence and Antitumor Activity
por: Durães, Fernando, et al.
Publicado: (2021)

Screening a Small Library of Xanthones for Antitumor Activity and Identification of a Hit Compound which Induces Apoptosis
por: Barbosa, João, et al.
Publicado: (2016)

Boronic Acids and Their Derivatives in Medicinal Chemistry: Synthesis and Biological Applications
por: Silva, Mariana Pereira, et al.
Publicado: (2020)

3,4-Dioxygenated xanthones as antifouling additives for marine coatings: in silico studies, seawater solubility, degradability, leaching, and antifouling performance
por: Vilas-Boas, Cátia, et al.
Publicado: (2023)

Antithrombotics from the Sea: Polysaccharides and Beyond
por: Carvalhal, Francisca, et al.
Publicado: (2019)

Natural Benzo/Acetophenones as Leads for New Synthetic Acetophenone Hybrids Containing a 1,2,3-Triazole Ring as Potential Antifouling Agents
por: Neves, Ana Rita, et al.
Publicado: (2021)

Prenylated Chalcone 2 Acts as an Antimitotic Agent and Enhances the Chemosensitivity of Tumor Cells to Paclitaxel
por: Fonseca, Joana, et al.
Publicado: (2016)

Progress and Achievements in Glycosylation of Flavonoids
por: Khodzhaieva, Ruslana S., et al.
Publicado: (2021)

BP-M345, a New Diarylpentanoid with Promising Antimitotic Activity
por: Novais, Pedro, et al.
Publicado: (2021)

Antifouling potential of Nature-inspired sulfated compounds
por: Almeida, Joana R., et al.
Publicado: (2017)

Three-Dimensional Spheroids as In Vitro Preclinical Models for Cancer Research
por: Pinto, Bárbara, et al.
Publicado: (2020)

Antifouling Marine Coatings with a Potentially Safer and Sustainable Synthetic Polyphenolic Derivative
por: Neves, Ana R., et al.
Publicado: (2022)

Chiral Thioxanthones as Modulators of P-glycoprotein: Synthesis and Enantioselectivity Studies
por: Lopes, Ana, et al.
Publicado: (2018)

Composition, anti-LDL oxidation, and non-enzymatic glycosylation inhibitory activities of the flavonoids from Mesembryanthemum crystallinum
por: Sun, Meiling, et al.
Publicado: (2022)

Chiral Flavonoids as Antitumor Agents
por: Pinto, Cláudia, et al.
Publicado: (2021)

Synthesis of a Small Library of Nature-Inspired Xanthones and Study of Their Antimicrobial Activity
por: Resende, Diana I. S. P., et al.
Publicado: (2020)

Quantification of a Sulfated Marine-Inspired Antifouling Compound in Several Aqueous Matrices: Biodegradation Studies and Leaching Assays from Polydimethylsiloxane Coatings
por: Vilas-Boas, Cátia, et al.
Publicado: (2022)

Isolation and Potential Biological Applications of Haloaryl Secondary Metabolites from Macroalgae
por: Jesus, Ana, et al.
Publicado: (2019)

Small Molecules of Marine Origin as Potential Anti-Glioma Agents
por: Alves, Ana, et al.
Publicado: (2021)

BUB3, beyond the Simple Role of Partner
por: Silva, Patrícia M. A., et al.
Publicado: (2022)

New Chalcone–Triazole Hybrids with Promising Antimicrobial Activity in Multidrug Resistance Strains
por: Pereira, Daniela, et al.
Publicado: (2022)

From Natural Products to New Synthetic Small Molecules: A Journey through the World of Xanthones
por: Pinto, Madalena M. M., et al.
Publicado: (2021)

Derivatives of Trimethoxybenzoic Acid and Gallic Acid as Potential Efflux Pump Inhibitors: In Silico and In Vitro Studies
por: Neves, Ana Rita, et al.
Publicado: (2022)

Combination Therapy as a Promising Way to Fight Oral Cancer
por: Silva, João P. N., et al.
Publicado: (2023)

Impact of Tralopyril and Triazolyl Glycosylated Chalcone in Human Retinal Cells’ Lipidome
por: Vilas-Boas, Cátia, et al.
Publicado: (2022)

1,2-Dihydroxyxanthone: Effect on A375-C5 Melanoma Cell Growth Associated with Interference with THP-1 Human Macrophage Activity
por: Silva, Viviana, et al.
Publicado: (2019)

Navitoclax Enhances the Therapeutic Effects of PLK1 Targeting on Lung Cancer Cells in 2D and 3D Culture Systems
por: Pinto, Bárbara, et al.
Publicado: (2022)

The Hallmarks of Flavonoids in Cancer
por: Ponte, Luis Gustavo Saboia, et al.
Publicado: (2021)

Semi-Synthesis of Small Molecules of Aminocarbazoles: Tumor Growth Inhibition and Potential Impact on p53
por: Long, Solida, et al.
Publicado: (2021)

Antagonizing the spindle assembly checkpoint silencing enhances paclitaxel and Navitoclax-mediated apoptosis with distinct mechanistic
por: Henriques, Ana C., et al.
Publicado: (2021)

Marine Natural Products, Multitarget Therapy and Repurposed Agents in Alzheimer’s Disease
por: Martins, Márcia, et al.
Publicado: (2020)

Synthesis and Evaluation of the Acetylcholinesterase Inhibitory Activities of Some Flavonoids Derived from Naringenin
por: Tran, The-Huan, et al.
Publicado: (2021)

Synthesis of New Proteomimetic Quinazolinone Alkaloids and Evaluation of Their Neuroprotective and Antitumor Effects
por: Long, Solida, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_0uss3cm3pvfit21bj71sihjvtm