Preferential and Increased Uptake of Hydroxyl-Terminated PAMAM Dendrimers by Activated Microglia in Rabbit Brain Mixed Glial Culture

Polyamidoamine (PAMAM) dendrimers are multifunctional nanoparticles with tunable physicochemical features, making them promising candidates for targeted drug delivery in the central nervous system (CNS). Systemically administered dendrimers have been shown to localize in activated glial cells, which...

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Detalles Bibliográficos
Autores principales: Alnasser, Yossef, Kambhampati, Siva P., Nance, Elizabeth, Rajbhandari, Labchan, Shrestha, Shiva, Venkatesan, Arun, Kannan, Rangaramanujam M., Kannan, Sujatha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6102539/
https://www.ncbi.nlm.nih.gov/pubmed/29702566
http://dx.doi.org/10.3390/molecules23051025

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