To ERV Is Human: A Phenotype-Wide Scan Linking Polymorphic Human Endogenous Retrovirus-K Insertions to Complex Phenotypes

Approximately 8% of the human genome is comprised of endogenous retroviral insertions (ERVs) originating from historic retroviral integration into germ cells. The function of ERVs as regulators of gene expression is well established. Less well studied are insertional polymorphisms of ERVs and their...

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Detalles Bibliográficos
Autores principales: Wallace, Amelia D., Wendt, George A., Barcellos, Lisa F., de Smith, Adam J., Walsh, Kyle M., Metayer, Catherine, Costello, Joseph F., Wiemels, Joseph L., Francis, Stephen S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6102640/
https://www.ncbi.nlm.nih.gov/pubmed/30154825
http://dx.doi.org/10.3389/fgene.2018.00298

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