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Emodin alleviates CCl4-induced liver fibrosis by suppressing epithelial-mesenchymal transition and transforming growth factor-β1 in rats

Liver fibrosis is a chronic disease that exhibits a complicated pathophysiology. It is characterized by the deposition of the extracellular matrix. Emodin, an active constituent isolated from rhubarb, has antibacterial, immunosuppressive and anti-inflammatory effects. In the present study, the mecha...

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Detalles Bibliográficos
Autores principales: Liu, Feng, Zhang, Jing, Qian, Jianmin, Wu, Gang, Ma, Zhenyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6102702/
https://www.ncbi.nlm.nih.gov/pubmed/30066878
http://dx.doi.org/10.3892/mmr.2018.9324