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SH2B1 protects against OGD/R-induced apoptosis in PC12 cells via activation of the JAK2/STAT3 signaling pathway

Apoptosis acts as the primary pathogenesis of cerebral ischemia/reperfusion (I/R) injury. Prior studies have revealed the effects of src homology 2 (SH2)B adaptor protein 1 (SH2B1) in myocardial infarction; however, involvement of SH2B1 in cerebral I/R injury and the underlying mechanisms remain to...

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Detalles Bibliográficos
Autores principales:	Yuan, Jiang, Zeng, Lei, Sun, Yanpeng, Wang, Na, Sun, Qiang, Cheng, Zhaohui, Wang, Yunfu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2018
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6102733/ https://www.ncbi.nlm.nih.gov/pubmed/30015896 http://dx.doi.org/10.3892/mmr.2018.9265

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