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Exendin-4 reverses endothelial dysfunction in mice fed a high-cholesterol diet by a GTP cyclohydrolase-1/tetrahydrobiopterin pathway

The present study examined whether exendin-4 (Ex4) can improve the endothelial dysfunction of apolipoprotein E knockout (APOE-KO) mice fed a high-cholesterol diet and the potential mechanism by which it acts. Genetically wild-type (WT) C57BL/6 mice and APOE-KO mice of C57BL/6 background, were each r...

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Detalles Bibliográficos
Autores principales:	Tang, Zhiqi, Liu, Lijuan, Guo, Yujie, Deng, Guoxiong, Chen, Meixiang, Wei, Jinru
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2018
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6102738/ https://www.ncbi.nlm.nih.gov/pubmed/30085331 http://dx.doi.org/10.3892/mmr.2018.9345

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