Cargando…
Kaempferol inhibits interleukin-1β stimulated matrix metalloproteinases by suppressing the MAPK-associated ERK and P38 signaling pathways
Osteoarthritis (OA) is a common degenerative joint disease in older adults. A number of previous studies have demonstrated that natural flavonoids can serve as promising therapeutic drugs for OA. Kaempferol, a phytochemical ingredient mainly present in various fruits, has exhibited its prominent ant...
Autores principales: | Huang, Xiaojian, Pan, Qiyong, Mao, Zekai, Wang, Pengcheng, Zhang, Rui, Ma, Xiaohu, Chen, Jingyuan, You, Hongbo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6102739/ https://www.ncbi.nlm.nih.gov/pubmed/30015923 http://dx.doi.org/10.3892/mmr.2018.9280 |
Ejemplares similares
-
Histone deacetylase-4 and histone deacetylase-8 regulate interleukin-1β-induced cartilage catabolic degradation through MAPK/JNK and ERK pathways
por: Wang, Pengcheng, et al.
Publicado: (2018) -
Chondro-Protective Effects of Shikimic Acid on Osteoarthritis via Restoring Impaired Autophagy and Suppressing the MAPK/NF-κB Signaling Pathway
por: You, Hongbo, et al.
Publicado: (2021) -
Camel Milk Mitigates Cyclosporine-Induced Renal Damage in Rats: Targeting p38/ERK/JNK MAPKs, NF-κB, and Matrix Metalloproteinases
por: Arab, Hany H., et al.
Publicado: (2021) -
HGF potentiates extracellular matrix-driven migration of human myoblasts: involvement of matrix metalloproteinases and MAPK/ERK pathway
por: González, Mariela Natacha, et al.
Publicado: (2017) -
Kaempferol Reduces Matrix Metalloproteinase-2 Expression by Down-Regulating ERK1/2 and the Activator Protein-1 Signaling Pathways in Oral Cancer Cells
por: Lin, Chiao-Wen, et al.
Publicado: (2013)