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RIP3 dependent NLRP3 inflammasome activation is implicated in acute lung injury in mice

BACKGROUND: NLRP3 inflammasome is involved in the inflammatory responses during acute lung injury (ALI). RIP3 triggered NLRP3 inflammasome activation independent of necroptosis induction has recently been documented. In this study, the role of RIP3 in the activation of NLRP3 inflammasome in the deve...

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Detalles Bibliográficos
Autores principales: Chen, Jingxian, Wang, Shuang, Fu, Rong, Zhou, Mianjing, Zhang, Tengyue, Pan, Wenxu, Yang, Niansheng, Huang, Yuefang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6102827/
https://www.ncbi.nlm.nih.gov/pubmed/30126430
http://dx.doi.org/10.1186/s12967-018-1606-4