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Subretinal macrophages produce classical complement activator C1q leading to the progression of focal retinal degeneration

BACKGROUND: The role of the alternative complement pathway and its mediation by retinal microglia and macrophages, is well-established in the pathogenesis of Age-Related Macular Degeneration (AMD). However, the contribution of the classical complement pathway towards the progression of retinal degen...

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Detalles Bibliográficos
Autores principales:	Jiao, Haihan, Rutar, Matt, Fernando, Nilisha, Yednock, Ted, Sankaranarayanan, Sethu, Aggio-Bruce, Riemke, Provis, Jan, Natoli, Riccardo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6102844/ https://www.ncbi.nlm.nih.gov/pubmed/30126455 http://dx.doi.org/10.1186/s13024-018-0278-0

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