Cargando…
Spectrum of opportunistic infections and associated factors among people living with HIV/AIDS in the era of highly active anti-retroviral treatment in Dawro Zone hospital: a retrospective study
OBJECTIVES: The study aims to elucidate the spectrum, magnitude and determining factors of the major opportunistic infections in PLHIV patients currently receiving HAART. RESULTS: A retrospective cross-sectional study was conducted at Tercha Hospital from 744 patient cards. The overall all prevalenc...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6102885/ https://www.ncbi.nlm.nih.gov/pubmed/30126450 http://dx.doi.org/10.1186/s13104-018-3707-9 |
_version_ | 1783349260567183360 |
---|---|
author | Solomon, Fithamlak Bistegen Angore, Banchalem Nega Koyra, Hailu Chare Tufa, Efrata Girma Berheto, Tezera Moshago Admasu, Mahlet |
author_facet | Solomon, Fithamlak Bistegen Angore, Banchalem Nega Koyra, Hailu Chare Tufa, Efrata Girma Berheto, Tezera Moshago Admasu, Mahlet |
author_sort | Solomon, Fithamlak Bistegen |
collection | PubMed |
description | OBJECTIVES: The study aims to elucidate the spectrum, magnitude and determining factors of the major opportunistic infections in PLHIV patients currently receiving HAART. RESULTS: A retrospective cross-sectional study was conducted at Tercha Hospital from 744 patient cards. The overall all prevalence of opportunistic infection was 658 (88.4%) developed OIs. Pulmonary tuberculosis, 118 (18%), severe community acquired pneumonia 107 (16.3%) and oral candidiasis 103 (15.6%) were the most common opportunistic infections. Disease stage [AOR = 3.22:95% CI 1.76–5.66], CD4 level [AOR = 2.53:95% CI 1.19–5.37], drug adherence [AOR = 3.02:95% CI 1.57–5.77] and hemoglobin [AOR = 2.49:95% CI 1.34–4.62] showed significant association with OIs. Higher magnitude of opportunistic infection with considerable proportion of AIDS defining illness was detected. So empowerment of skilled man power, health education and provision of antimicrobials is mandatory. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s13104-018-3707-9) contains supplementary material, which is available to authorized users. |
format | Online Article Text |
id | pubmed-6102885 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-61028852018-08-27 Spectrum of opportunistic infections and associated factors among people living with HIV/AIDS in the era of highly active anti-retroviral treatment in Dawro Zone hospital: a retrospective study Solomon, Fithamlak Bistegen Angore, Banchalem Nega Koyra, Hailu Chare Tufa, Efrata Girma Berheto, Tezera Moshago Admasu, Mahlet BMC Res Notes Research Note OBJECTIVES: The study aims to elucidate the spectrum, magnitude and determining factors of the major opportunistic infections in PLHIV patients currently receiving HAART. RESULTS: A retrospective cross-sectional study was conducted at Tercha Hospital from 744 patient cards. The overall all prevalence of opportunistic infection was 658 (88.4%) developed OIs. Pulmonary tuberculosis, 118 (18%), severe community acquired pneumonia 107 (16.3%) and oral candidiasis 103 (15.6%) were the most common opportunistic infections. Disease stage [AOR = 3.22:95% CI 1.76–5.66], CD4 level [AOR = 2.53:95% CI 1.19–5.37], drug adherence [AOR = 3.02:95% CI 1.57–5.77] and hemoglobin [AOR = 2.49:95% CI 1.34–4.62] showed significant association with OIs. Higher magnitude of opportunistic infection with considerable proportion of AIDS defining illness was detected. So empowerment of skilled man power, health education and provision of antimicrobials is mandatory. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s13104-018-3707-9) contains supplementary material, which is available to authorized users. BioMed Central 2018-08-20 /pmc/articles/PMC6102885/ /pubmed/30126450 http://dx.doi.org/10.1186/s13104-018-3707-9 Text en © The Author(s) 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Research Note Solomon, Fithamlak Bistegen Angore, Banchalem Nega Koyra, Hailu Chare Tufa, Efrata Girma Berheto, Tezera Moshago Admasu, Mahlet Spectrum of opportunistic infections and associated factors among people living with HIV/AIDS in the era of highly active anti-retroviral treatment in Dawro Zone hospital: a retrospective study |
title | Spectrum of opportunistic infections and associated factors among people living with HIV/AIDS in the era of highly active anti-retroviral treatment in Dawro Zone hospital: a retrospective study |
title_full | Spectrum of opportunistic infections and associated factors among people living with HIV/AIDS in the era of highly active anti-retroviral treatment in Dawro Zone hospital: a retrospective study |
title_fullStr | Spectrum of opportunistic infections and associated factors among people living with HIV/AIDS in the era of highly active anti-retroviral treatment in Dawro Zone hospital: a retrospective study |
title_full_unstemmed | Spectrum of opportunistic infections and associated factors among people living with HIV/AIDS in the era of highly active anti-retroviral treatment in Dawro Zone hospital: a retrospective study |
title_short | Spectrum of opportunistic infections and associated factors among people living with HIV/AIDS in the era of highly active anti-retroviral treatment in Dawro Zone hospital: a retrospective study |
title_sort | spectrum of opportunistic infections and associated factors among people living with hiv/aids in the era of highly active anti-retroviral treatment in dawro zone hospital: a retrospective study |
topic | Research Note |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6102885/ https://www.ncbi.nlm.nih.gov/pubmed/30126450 http://dx.doi.org/10.1186/s13104-018-3707-9 |
work_keys_str_mv | AT solomonfithamlakbistegen spectrumofopportunisticinfectionsandassociatedfactorsamongpeoplelivingwithhivaidsintheeraofhighlyactiveantiretroviraltreatmentindawrozonehospitalaretrospectivestudy AT angorebanchalemnega spectrumofopportunisticinfectionsandassociatedfactorsamongpeoplelivingwithhivaidsintheeraofhighlyactiveantiretroviraltreatmentindawrozonehospitalaretrospectivestudy AT koyrahailuchare spectrumofopportunisticinfectionsandassociatedfactorsamongpeoplelivingwithhivaidsintheeraofhighlyactiveantiretroviraltreatmentindawrozonehospitalaretrospectivestudy AT tufaefratagirma spectrumofopportunisticinfectionsandassociatedfactorsamongpeoplelivingwithhivaidsintheeraofhighlyactiveantiretroviraltreatmentindawrozonehospitalaretrospectivestudy AT berhetotezeramoshago spectrumofopportunisticinfectionsandassociatedfactorsamongpeoplelivingwithhivaidsintheeraofhighlyactiveantiretroviraltreatmentindawrozonehospitalaretrospectivestudy AT admasumahlet spectrumofopportunisticinfectionsandassociatedfactorsamongpeoplelivingwithhivaidsintheeraofhighlyactiveantiretroviraltreatmentindawrozonehospitalaretrospectivestudy |