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Spectrum of opportunistic infections and associated factors among people living with HIV/AIDS in the era of highly active anti-retroviral treatment in Dawro Zone hospital: a retrospective study

OBJECTIVES: The study aims to elucidate the spectrum, magnitude and determining factors of the major opportunistic infections in PLHIV patients currently receiving HAART. RESULTS: A retrospective cross-sectional study was conducted at Tercha Hospital from 744 patient cards. The overall all prevalenc...

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Autores principales: Solomon, Fithamlak Bistegen, Angore, Banchalem Nega, Koyra, Hailu Chare, Tufa, Efrata Girma, Berheto, Tezera Moshago, Admasu, Mahlet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6102885/
https://www.ncbi.nlm.nih.gov/pubmed/30126450
http://dx.doi.org/10.1186/s13104-018-3707-9
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author Solomon, Fithamlak Bistegen
Angore, Banchalem Nega
Koyra, Hailu Chare
Tufa, Efrata Girma
Berheto, Tezera Moshago
Admasu, Mahlet
author_facet Solomon, Fithamlak Bistegen
Angore, Banchalem Nega
Koyra, Hailu Chare
Tufa, Efrata Girma
Berheto, Tezera Moshago
Admasu, Mahlet
author_sort Solomon, Fithamlak Bistegen
collection PubMed
description OBJECTIVES: The study aims to elucidate the spectrum, magnitude and determining factors of the major opportunistic infections in PLHIV patients currently receiving HAART. RESULTS: A retrospective cross-sectional study was conducted at Tercha Hospital from 744 patient cards. The overall all prevalence of opportunistic infection was 658 (88.4%) developed OIs. Pulmonary tuberculosis, 118 (18%), severe community acquired pneumonia 107 (16.3%) and oral candidiasis 103 (15.6%) were the most common opportunistic infections. Disease stage [AOR = 3.22:95% CI 1.76–5.66], CD4 level [AOR = 2.53:95% CI 1.19–5.37], drug adherence [AOR = 3.02:95% CI 1.57–5.77] and hemoglobin [AOR = 2.49:95% CI 1.34–4.62] showed significant association with OIs. Higher magnitude of opportunistic infection with considerable proportion of AIDS defining illness was detected. So empowerment of skilled man power, health education and provision of antimicrobials is mandatory. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s13104-018-3707-9) contains supplementary material, which is available to authorized users.
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spelling pubmed-61028852018-08-27 Spectrum of opportunistic infections and associated factors among people living with HIV/AIDS in the era of highly active anti-retroviral treatment in Dawro Zone hospital: a retrospective study Solomon, Fithamlak Bistegen Angore, Banchalem Nega Koyra, Hailu Chare Tufa, Efrata Girma Berheto, Tezera Moshago Admasu, Mahlet BMC Res Notes Research Note OBJECTIVES: The study aims to elucidate the spectrum, magnitude and determining factors of the major opportunistic infections in PLHIV patients currently receiving HAART. RESULTS: A retrospective cross-sectional study was conducted at Tercha Hospital from 744 patient cards. The overall all prevalence of opportunistic infection was 658 (88.4%) developed OIs. Pulmonary tuberculosis, 118 (18%), severe community acquired pneumonia 107 (16.3%) and oral candidiasis 103 (15.6%) were the most common opportunistic infections. Disease stage [AOR = 3.22:95% CI 1.76–5.66], CD4 level [AOR = 2.53:95% CI 1.19–5.37], drug adherence [AOR = 3.02:95% CI 1.57–5.77] and hemoglobin [AOR = 2.49:95% CI 1.34–4.62] showed significant association with OIs. Higher magnitude of opportunistic infection with considerable proportion of AIDS defining illness was detected. So empowerment of skilled man power, health education and provision of antimicrobials is mandatory. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s13104-018-3707-9) contains supplementary material, which is available to authorized users. BioMed Central 2018-08-20 /pmc/articles/PMC6102885/ /pubmed/30126450 http://dx.doi.org/10.1186/s13104-018-3707-9 Text en © The Author(s) 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Note
Solomon, Fithamlak Bistegen
Angore, Banchalem Nega
Koyra, Hailu Chare
Tufa, Efrata Girma
Berheto, Tezera Moshago
Admasu, Mahlet
Spectrum of opportunistic infections and associated factors among people living with HIV/AIDS in the era of highly active anti-retroviral treatment in Dawro Zone hospital: a retrospective study
title Spectrum of opportunistic infections and associated factors among people living with HIV/AIDS in the era of highly active anti-retroviral treatment in Dawro Zone hospital: a retrospective study
title_full Spectrum of opportunistic infections and associated factors among people living with HIV/AIDS in the era of highly active anti-retroviral treatment in Dawro Zone hospital: a retrospective study
title_fullStr Spectrum of opportunistic infections and associated factors among people living with HIV/AIDS in the era of highly active anti-retroviral treatment in Dawro Zone hospital: a retrospective study
title_full_unstemmed Spectrum of opportunistic infections and associated factors among people living with HIV/AIDS in the era of highly active anti-retroviral treatment in Dawro Zone hospital: a retrospective study
title_short Spectrum of opportunistic infections and associated factors among people living with HIV/AIDS in the era of highly active anti-retroviral treatment in Dawro Zone hospital: a retrospective study
title_sort spectrum of opportunistic infections and associated factors among people living with hiv/aids in the era of highly active anti-retroviral treatment in dawro zone hospital: a retrospective study
topic Research Note
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6102885/
https://www.ncbi.nlm.nih.gov/pubmed/30126450
http://dx.doi.org/10.1186/s13104-018-3707-9
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