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Genome Rearrangement Shapes Prochlorococcus Ecological Adaptation
Prochlorococcus is the most abundant and smallest known free-living photosynthetic microorganism and is a key player in marine ecosystems and biogeochemical cycles. Prochlorococcus can be broadly divided into high-light-adapted (HL) and low-light-adapted (LL) clades. In this study, we isolated two l...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6102989/ https://www.ncbi.nlm.nih.gov/pubmed/29915114 http://dx.doi.org/10.1128/AEM.01178-18 |
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author | Yan, Wei Wei, Shuzhen Wang, Qiong Xiao, Xilin Zeng, Qinglu Jiao, Nianzhi Zhang, Rui |
author_facet | Yan, Wei Wei, Shuzhen Wang, Qiong Xiao, Xilin Zeng, Qinglu Jiao, Nianzhi Zhang, Rui |
author_sort | Yan, Wei |
collection | PubMed |
description | Prochlorococcus is the most abundant and smallest known free-living photosynthetic microorganism and is a key player in marine ecosystems and biogeochemical cycles. Prochlorococcus can be broadly divided into high-light-adapted (HL) and low-light-adapted (LL) clades. In this study, we isolated two low-light-adapted clade I (LLI) strains from the western Pacific Ocean and obtained their genomic data. We reconstructed Prochlorococcus evolution based on genome rearrangement. Our results showed that genome rearrangement might have played an important role in Prochlorococcus evolution. We also found that the Prochlorococcus clades with streamlined genomes maintained relatively high synteny throughout most of their genomes, and several regions served as rearrangement hotspots. Backbone analysis showed that different clades shared a conserved backbone but also had clade-specific regions, and the genes in these regions were associated with ecological adaptations. IMPORTANCE Prochlorococcus, the most abundant and smallest known free-living photosynthetic microorganism, plays a key role in marine ecosystems and biogeochemical cycles. Prochlorococcus genome evolution is a fundamental issue related to how Prochlorococcus clades adapted to different ecological niches. Recent studies revealed that the gene gain and loss is crucial to the clade differentiation. The significance of our research is that we interpreted the Prochlorococcus genome evolution from the perspective of genome structure and associated the genome rearrangement with the Prochlorococcus clade differentiation and subsequent ecological adaptation. |
format | Online Article Text |
id | pubmed-6102989 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | American Society for Microbiology |
record_format | MEDLINE/PubMed |
spelling | pubmed-61029892018-08-31 Genome Rearrangement Shapes Prochlorococcus Ecological Adaptation Yan, Wei Wei, Shuzhen Wang, Qiong Xiao, Xilin Zeng, Qinglu Jiao, Nianzhi Zhang, Rui Appl Environ Microbiol Environmental Microbiology Prochlorococcus is the most abundant and smallest known free-living photosynthetic microorganism and is a key player in marine ecosystems and biogeochemical cycles. Prochlorococcus can be broadly divided into high-light-adapted (HL) and low-light-adapted (LL) clades. In this study, we isolated two low-light-adapted clade I (LLI) strains from the western Pacific Ocean and obtained their genomic data. We reconstructed Prochlorococcus evolution based on genome rearrangement. Our results showed that genome rearrangement might have played an important role in Prochlorococcus evolution. We also found that the Prochlorococcus clades with streamlined genomes maintained relatively high synteny throughout most of their genomes, and several regions served as rearrangement hotspots. Backbone analysis showed that different clades shared a conserved backbone but also had clade-specific regions, and the genes in these regions were associated with ecological adaptations. IMPORTANCE Prochlorococcus, the most abundant and smallest known free-living photosynthetic microorganism, plays a key role in marine ecosystems and biogeochemical cycles. Prochlorococcus genome evolution is a fundamental issue related to how Prochlorococcus clades adapted to different ecological niches. Recent studies revealed that the gene gain and loss is crucial to the clade differentiation. The significance of our research is that we interpreted the Prochlorococcus genome evolution from the perspective of genome structure and associated the genome rearrangement with the Prochlorococcus clade differentiation and subsequent ecological adaptation. American Society for Microbiology 2018-08-17 /pmc/articles/PMC6102989/ /pubmed/29915114 http://dx.doi.org/10.1128/AEM.01178-18 Text en Copyright © 2018 Yan et al. https://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Environmental Microbiology Yan, Wei Wei, Shuzhen Wang, Qiong Xiao, Xilin Zeng, Qinglu Jiao, Nianzhi Zhang, Rui Genome Rearrangement Shapes Prochlorococcus Ecological Adaptation |
title | Genome Rearrangement Shapes Prochlorococcus Ecological Adaptation |
title_full | Genome Rearrangement Shapes Prochlorococcus Ecological Adaptation |
title_fullStr | Genome Rearrangement Shapes Prochlorococcus Ecological Adaptation |
title_full_unstemmed | Genome Rearrangement Shapes Prochlorococcus Ecological Adaptation |
title_short | Genome Rearrangement Shapes Prochlorococcus Ecological Adaptation |
title_sort | genome rearrangement shapes prochlorococcus ecological adaptation |
topic | Environmental Microbiology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6102989/ https://www.ncbi.nlm.nih.gov/pubmed/29915114 http://dx.doi.org/10.1128/AEM.01178-18 |
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