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Macrophage-derived extracellular vesicles mediate smooth muscle hyperplasia: role of altered miRNA cargo in response to HIV infection and substance abuse

Our previous studies consistently demonstrate enhanced pulmonary vascular remodeling in HIV–infected intravenous drug users, and in simian immunodeficiency virus–infected macaques or HIV-transgenic rats exposed to opioids or cocaine. Although we reported an associated increase in perivascular inflam...

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Detalles Bibliográficos
Autores principales: Sharma, Himanshu, Chinnappan, Mahendran, Agarwal, Stuti, Dalvi, Pranjali, Gunewardena, Sumedha, O’Brien-Ladner, Amy, Dhillon, Navneet K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Federation of American Societies for Experimental Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6103174/
https://www.ncbi.nlm.nih.gov/pubmed/29672222
http://dx.doi.org/10.1096/fj.201701558R